| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| cerebral oedema | Brain swelling due to increased volume of the extravascular compartment from the uptake of water in the neuropile and white matter. See: brain swelling. Synonym: brain oedema. (05 Mar 2000) |
|---|---|
| reverse pulmonary oedema pattern | <radiology> Loeffler pneumonia, chronic eosinophilic pneumonia (12 Dec 1998) |
| menstrual oedema | Retention of water and increase in weight, which occurs during or preceding menstruation. (05 Mar 2000) |
| periodic oedema | A vascular reaction involving the deep dermis or subcutaneous or submucal tissues, representing localised oedema caused by dilatation and increased permeability of the capillaries and characterised by development of giant wheals. (18 Nov 1997) |
| pitting oedema | Oedema that retains for a time the indentation produced by pressure. (05 Mar 2000) |
| corneal oedema | An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity. (12 Dec 1998) |
| premenstrual oedema | Retention of water and increase in weight, which occurs during or preceding menstruation. (05 Mar 2000) |
| cystoid macular oedema | Oedema of the posterior pole of the eye secondary to abnormal permeability of capillaries of the central sensory retina. (05 Mar 2000) |
| heat oedema | Oedema caused by excessively high external temperature. (05 Mar 2000) |
| salt oedema | Oedema from excessive intake or retention of sodium chloride. (05 Mar 2000) |
| hereditary angioneurotic oedema | A genetic form of angioedema. (angioedema is also referred to as quinke's disease.) persons with it are born lacking an inhibitor protein (called c1 esterase inhibitor) that normally prevents activation of a cascade of proteins leading to the swelling of angioedema. Patients can develop recurrent attacks of swollen tissues, pain in the abdomen, and swelling of the voice box (larynx) which can compromise breathing. The diagnosis is suspected with a history of recurrent angioedema. It is confirmed by finding abnormally low levels of c1 esterase inhibitor in the blood. Treatment options include antihistamines and male steroids (androgens) that can also prevent the recurrent attacks. Also called hereditary angioedema. (12 Dec 1998) |
| hereditary angio oedema | <biochemistry> Condition in which there seems to be uncontrolled production of C2 kinin because of a deficiency in C1 inhibitor levels. (18 Nov 1997) |
| high altitude cerebral oedema | <physiology> A serious condition that results from the sudden increase in pressure within the brain due to swelling. This is thought to occur secondary to exposure to high altitudes, generally in excess of 12,000 feet. (12 Jan 1998) |
| high altitude pulmonary oedema | <physiology> The abnormal deposition of fluid into the lungs that occurs with exposure to lower barometric pressure and low oxygen. (12 Jan 1998) |
| pulmonary oedema | <cardiology> A severe state of increased interstitial fluid within the lung that leads to flooding of the alveoli with fluid. This results in a severe disturbance of gas exchange across the alveolar surface. Often results from the ineffective pump function of the heart (noncardiac causes also exist). (27 Sep 1997) |