| SAS | sarcoma amplified sequence; self-rating anxiety scale; short arm splint; Sklar Aphasia Scale; sleep ... |
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| SCC | self-care center; sequential combination chemotherapy; services for crippled children; short-course ... |
| CNK | cortical necrosis of kidneys |
| H-L-K | heart, liver, and kidneys |
| KLS | kidneys, liver, and spleen; Kreuzbein lipomatous syndrome |
| smooth muscle tissue | <anatomy, pathology, physiology> Muscle tissue in vertebrates made up from long tapering cells that may be anything from 20-500m long. Smooth muscle is generally involuntary and differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. Smooth muscle cells are found particularly in blood vessel walls, surrounding the intestine (particularly the gizzard in birds) and in the uterus. The contractile system and its control resemble those of motile tissue cells (e.g. Fibroblasts, leucocytes) and antibodies against smooth muscle myosin will cross react with myosin from tissue cells, whereas antibodies against skeletal muscle myosin will not. See: dense bodies. (18 Nov 1997) |
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| smooth muscle tumour | A tumour composed of smooth muscle tissue, as opposed to leiomyoma, a tumour derived from smooth muscle. (12 Dec 1998) |
| smooth muscular sphincter | A sphincter of smooth musculature. Synonym: smooth muscular sphincter. Origin: G. Lissos, smooth, + sphincter (05 Mar 2000) |
| smooth strain | <microbiology> Bacterial strains that have altered outer cell wall carbohydrate chains causing colonies on agar to change their appearance from smooth to dull. In Streptococci the smooth strains are virulent whereas the rough strains are not. This is partly because the rough strains are much more readily phagocytosed. (17 Dec 1997) |
| smooth surface caries | Caries initiated on the smooth surfaces of teeth. (05 Mar 2000) |
| smooth-surfaced endoplasmic reticulum | Endoplasmic reticulum that is lacking in ribosomal granules; involved in synthesis of complex lipids and fatty acids, detoxification of drugs, carbohydrate synthesis, and sequestering of Ca++. Synonym: smooth-surfaced endoplasmic reticulum. (05 Mar 2000) |
| endoplasmic reticulum, smooth | A type of endoplasmic reticulum lacking associated ribosomes on the membrane surface. It exhibits a wide range of specialised metabolic functions including supplying enzymes for steroid synthesis, detoxification, and glycogen breakdown. In muscle cells, smooth endoplasmic reticulum is called sarcoplasmic reticulum. (12 Dec 1998) |
| carcinoma, non-small-cell lung | A heterogeneous aggregate of at least three distinct histological types of lung cancer, including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. They are dealt with collectively because of the shared properties of poor response to conventional chemotherapy and the potential for cure with surgical resection in a fraction of patients. (12 Dec 1998) |
| carcinoma, small cell | An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterised by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. There are admixtures of small cell lung carcinoma with other types of lung cancer. Small cell carcinomas are distinguished by their distinctive biological features, response to chemotherapy and radiotherapy, and by their nearly universal tendency to develop overt or subclinical metastases, which frequently eliminates surgery in most patients. (12 Dec 1998) |
| generalised small bowel disease | <radiology> Hypoproteinaemia, sprue, Whipple (12 Dec 1998) |
| mesenteric portion of small intestine | The freely movable portion of the small intestine supplied with a mesentery, comprising the jejunum and ileum. Synonym: mesenteric portion of small intestine. (05 Mar 2000) |
| ribonucleoproteins, small nuclear | Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm. The u3 snrnp is localised in the nucleolus, where it aligns into base pairs with the 28s rrna precursor in a still unidentified region and functions in pre-rrna processing. The u7 snrnp aligns into base pairs with a conserved sequence in the 3'-end of histone pre-mRNA and is an essential cofactor for the cleavage that creates the mature nonadenylated 3'-end. (12 Dec 1998) |
| ribonucleoproteins, small, u1 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u1 snrnp along with other small ribonucleoproteins (u2, u4-u6, and u5) assemble into spliceosomes that remove introns from pre-mRNA by splicing. The u1 snrnp base pairs with conserved sequence motifs at the 5'-splice site and recognises both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction. (12 Dec 1998) |
| ribonucleoproteins, small, u2 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u2 snrnp along with other small ribonucleoproteins (u1, u4-u6, and u5) assemble into spliceosomes that remove introns from pre-mRNA by splicing. The u2 snrnp base pairs with conserved sequence motifs at the branch point, which associates with a heat- and rnaase-sensitive factor in an early step of splicing. (12 Dec 1998) |
| ribonucleoproteins, small, u4-u6 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u4-u6 snrnp along with the u5 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to form mature spliceosomes. There is also evidence for the existence of individual u4 or u6 snrnps in addition to their organization as a u4-u6 snrnp. (12 Dec 1998) |