| antihemophilic globulin B | <chemical> Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, ixa, forms a complex with factor viii and calcium on platelet factor 3 to activate factor x to xa. Deficiency of factor ix results in christmas disease (haemophilia b). Chemical name: Blood-coagulation factor IX (12 Dec 1998) |
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| antihuman globulin | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| antilymphocyte globulin | <protein> Antibodies which attach to and destroy lymphocytes. This may be used clinically by injection into a vein, for example in aplastic anaemia. (13 Nov 1997) |
| b1C globulin | The third component (C3) of complement. See: component of complement. (05 Mar 2000) |
| b1E globulin | The fourth component (C4) of complement. See: component of complement. (05 Mar 2000) |
| b1F globulin | The fifth component (C5) of complement. See: component of complement. (05 Mar 2000) |
| rabies immune globulin | Globulin fraction of pooled plasma of high anti-rabies virus titre from immunised persons. Synonym: rabies immunoglobulin. (05 Mar 2000) |
| gamma globulin | <immunology> A non-specific immunoglobulin (antibody) administered for the purpose of passive immunity. A common example is hepatitis A prophylaxis. (27 Sep 1997) |
| measles immune globulin | A sterile solution of globulin's derived from the blood plasma of normal adult human donors; it is prepared from immune serum globulin that complies with the measles antibody reference standard; a passive immunizing agent. Synonym: measles immunoglobulin. (05 Mar 2000) |
| globulin | <protein> A simple globular protein which cannot be dissolved in pure water but which can be dissolved if a salt is added to the water. It can also be precipitated out of solution and into a solid with a solution of ammonium sulphate at 50% saturation. Examples of globulin proteins are immunoglobulin and cryoglobulin. (14 Oct 1997) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| rho(d) immune globulin | Immunizing agent containing IgG anti-rho(d) used for preventing rh immunization in rh-negative individuals exposed to rh-positive red blood cells. (12 Dec 1998) |
| chickenpox immune globulin | Globulin fraction of serum from persons recently recovered from herpes zoster infection; used to prevent infection of high-risk children. Synonym: chickenpox immunoglobulin. (05 Mar 2000) |
| pertussis immune globulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| cold insoluble globulin | <haematology> Name, now obsolete, originally given to fibronectin prepared from cryoprecipitate. (18 Nov 1997) |