| basic proteins | Proteins that are rich in basic amino acids; e.g., histones. (05 Mar 2000) |
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| basic reaction | Any test by which an alkaline reaction is recognised, such as the change of red litmus paper to blue, an excess of hydroxide ions over hydrogen ions in aqueous solution as indicated by a pH value greater than 7 (at 22캜). Compare: dissociation constant of water. Synonym: basic reaction. (05 Mar 2000) |
| basic reproductive rate, ratio | <epidemiology> See Reproductive Ratio. (05 Dec 1998) |
| basic salt | A salt in which there are one or more hydroxyl ions not replaced by the electronegative element of an acid; e.g., Fe(OH)2Cl. (05 Mar 2000) |
| basic stain | <technique> A dye in which the cation is the coloured component of the dye molecule that binds to anionic groups of nucleic acids (PO4≡) or acidic mucopolysaccharides (e.g., chondroitin sulfate). (05 Mar 2000) |
| platelet basic protein | <protein> Protein that is the precursor of connective tissue activating peptide III and _ thromboglobulin. (18 Nov 1997) |
| myelin basic protein | <protein> Major component of the myelin sheath in mammalian CNS. Used as an antigen will induce a allergic encephalitis, possibly a model for some neurodegenerative disorders. (18 Nov 1997) |
| myelin basic protein kinase | <enzyme> Protein from pig brain activates ATP-mg-dependent protein phosphatase; a protein tau kinase; a multisubstrate kinase; in texts written as f subscript a Registry number: EC 2.7.1.- Synonym: protein phosphatase activator fa, glycogen synthase kinase 3, protein kinase f(a), gsk-3, gsk-3alpha, kinase f(a), gsk-3beta, mds1 gene product, p63(samk), src-activated mbp kinase, p63(mapk) (26 Jun 1999) |
| myelin basic proteins | A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (mbp) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (encephalomyelitis, allergic). In the peripheral nervous system, myelin basic protein 18.5 kD is often referred to as the p1 protein. (12 Dec 1998) |
| haematoxylin-malachite green-basic fuchsin stain | <technique> A stain for epoxy resin-extracted sections; semi-thick sections have their plastic dissolved out and the residual tissue is stained sequentially with the various dyes; nuclei and astrocytes are purplish-pink and myelin, lipid droplets, nucleoli, and oligodendrocytes are bright blue-green. (05 Mar 2000) |
| fibroblast growth factor, basic | A single-chain polypeptide of approximately 15-16 kD which has been isolated from a variety of cells. It has a 55% amino acid residue identity to acidic fibroblast growth factor and has potent heparin-binding activity. However, in contrast to the acidic fibroblast growth factor, heparin does not potentiate the biological activities of bfgf. The growth factor is an extremely potent inducer of DNA synthesis in a variety of normal diploid mammalian cell types from mesoderm and neuroectoderm lineages and promotes cellular differentiation in vitro. (12 Dec 1998) |
| acquired platelet function defect | <haematology> Platelet function can be affected by a number of different disease processes including polycythaemia vera, leukaemia, myelofibrosis, renal failure, multiple myeloma and some medications (for example penicillins, salicylates, phenothiazines). Disturbed blood clotting can be manifested by: easy bruising, bleeding gums, nosebleeds, abnormal vaginal bleeding, rectal bleeding, skin rash, vomiting blood, coughing up blood or blood in the urine. A measure of bleeding time and coagulation profile will be part of the evaluation. (29 Dec 1997) |
| aortic septal defect | A small congenital opening between the aorta and pulmonary artery about 1 cm above the semilunar valves, e.g., aorticopulmonary window. Synonym: aorticopulmonary window. (05 Mar 2000) |
| aortopulmonary septal defect | A congenital anomaly in which there is abnormal communication between the ascending aorta and pulmonary artery just above the semilunar valves. (12 Dec 1998) |
| atrial septal defect | <cardiology> An inherited condition where there is nonclosure of the foramen ovale at birth, resulting in congenital heart disease. Usually asymptomatic until the third or fourth decades of life. Symptoms include exertional shortness of breath, fatigue and palpitations. Acronym: ASD (12 Jan 1998) |