| CD | cadaver donor; canine distemper; canine dose; carbohydrate dehydratase; carbon dioxide; cardiac dise... |
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| MAIPA | Monoclonal Antibody-specific Immobilisation of Platelet Antigens |
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| antigens, CD28 | <immunology> T-cell differentiation antigens that serve as the receptors for the b7 antigen (antigens, CD80) which modulates T-cell lymphokine production. (12 Dec 1998) |
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| antigens, CD29 | <immunology> Integrin beta-1 chains which are expresssed as heterodimers noncovalently associated with specific alpha-chains of the CD49 family (CD49a-f). Cd29 is expressed on resting and activated leukocytes and is a marker for total very late activation antigens on cells. (barclay et al., the leukocyte antigen factsbook, 1993, p164) (12 Dec 1998) |
| antigens, CD3 | <immunology> A complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (receptors, antigen, T-cell). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (receptors, antigen, T-cell, gamma-delta). (12 Dec 1998) |
| antigens, CD30 | <immunology> Differentiation antigens normally present in a small number of cells in the lymph nodes and tonsils in vivo, but also capable of being induced in a wide range of cells in vitro. They are clinically useful as tumour markers for ki-1 lymphoma (lymphoma, large-cell, ki-1) and some cases of lymphomatoid papulosis, mycosis fungoides, and hodgkin's disease. (12 Dec 1998) |
| antigens, CD31 | <immunology> Cell adhesion molecules present on virtually all monocytes, platelets, and granulocytes. Cd31 is highly expressed on endothelial cells and concentrated at the junctions between them. (12 Dec 1998) |
| antigens, CD34 | <immunology> Glycoproteins found on immature haematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow. (12 Dec 1998) |
| antigens, CD36 | <immunology> Leukocyte differentiation antigens and major platelet membrane glycoproteins present on monocytes, endothelial cells, platelets, mammary epithelial cells, and a variety of cultured cell lines. They play major roles in adhesion phenomena, signal transduction, and haematopathology. Cd36 is also the receptor for thrombospondin and malaria-infected erythrocytes. (12 Dec 1998) |
| antigens, CD4 | <immunology> 55-kD glycoproteins originally defined as differentiation antigens on T-lymphocytes, but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (major histocompatibility complex) class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. Cd4 antigens also serve as HIV receptors, binding directly to the envelope protein gp120 on HIV. The protein structure on the surface of a human cell that allows HIV to attach, enter, and thus infect a cell. CD4 receptors are present on CD4 cells (helper T-cells), macrophages and dendritic cells, among others. Normally, CD4 acts as an accessory molecule, forming part of larger structures (such as the T-cell receptor) through which Tcells and other cells signal each other. (12 Dec 1998) |
| antigens, CD40 | <immunology> Differentiation antigens found on all mature B-lymphocytes and some epithelial cells, carcinomas, and lymphoid dendritic cells. This is a member of the tumour necrosis factor superfamily. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centres. (12 Dec 1998) |
| antigens, CD44 | <immunology> Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell types including mature T-cells, B-cells, medullary thymocytes, granulocytes, macrophages, erythrocytes, and fibroblasts. Cd44 antigens are the principle cell surface receptors for hyaluronate and this interaction mediates binding of lymphocytes to high endothelial venules. (12 Dec 1998) |
| antigens, CD45 | <immunology> High-molecular weight glycoproteins uniquely expressed on the surface of all leukocytes and their haemopoietic progenitors. The CD45 family consists of multiple members that are all products of a single gene. Cd45 expression is necessary for signalling through the T-cell receptor. (12 Dec 1998) |
| antigens, CD5 | <immunology> Glycoproteins expressed on all mature T-cells, thymocytes, and a subset of mature B-cells. Antibodies specific for CD5 can enhance T-cell receptor-mediated T-cell activation. The B-cell-specific molecule CD72 is a natural ligand for CD5. (12 Dec 1998) |
| antigens, CD55 | <immunology> Glycoproteins broadly distributed among haematopoietic and non-haematopoietic cells. Cd55 prevents the assembly of c3 convertase or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex. (12 Dec 1998) |
| antigens, CD56 | <immunology> The 140-kD isoform of ncam (neural cell adhesion molecule) containing a transmembrane domain and short cytoplasmic tail. It is expressed by all lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumours. (12 Dec 1998) |
| antigens, CD57 | <immunology> Oligosaccharide antigenic determinants found principally on nk cells and T-cells. Their role in the immune response is poorly understood. (12 Dec 1998) |
| hepatitis b surface antigens | Those hepatitis b antigens found on the surface of the dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen. (12 Dec 1998) |
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| hepatitis c antigens | Antigens of the virions of hepatitis c-like viruses, their surface, core, or other associated antigens. (12 Dec 1998) |
| histocompatibility antigens | A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection. (12 Dec 1998) |
| histocompatibility antigens class I | Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-a, HLA-b and HLA-c antigens. In mice, three genes named k, d, and l on chromosome 17 code for the h-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognised during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders. (12 Dec 1998) |
| histocompatibility antigens class II | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-d antigens and are coded by a gene on chromosome 6. In mice, two genes named ia and i.e. On chromosome 17 code for the h-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term ia antigens used to refer only to the proteins encoded by the ia genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. (12 Dec 1998) |
| HIV antigens | Antigens associated with specific proteins of the human adult T-cell immunodeficiency virus (HIV); also called HTLV-III-associated and lymphadenopathy-associated virus (lav) antigens. (12 Dec 1998) |
| HLA-a antigens | <immunology> Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. at least 20 antigens have been identified which are encoded by the a locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts. (12 Dec 1998) |
| HLA antigens | <immunology> A complex family of genetically inherited proteins which are found on the surface of cells throughout the body. They determine the match between patient and potential donor in bone marrow transplantation. These factors are inherited from the mother and father and so the chance of having the same HLA antigens between siblings is 1 in 4. See: human lymphocyte antigens. (20 Jun 2000) |
| HLA-b antigens | <immunology> Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus b of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-b27, -b7, -b8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic t lymphocytes. (12 Dec 1998) |
| HLA-c antigens | <immunology> Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the c locus on chromosome 6. They have significantly lower immunogenicity than the HLA-a and -b determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma). (12 Dec 1998) |
| HLA-d antigens | <immunology> Human immune-response or class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-d locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -dr, -dq and -dp designations, of which HLA-dr is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune aetiology. (12 Dec 1998) |
| HLA-dp antigens | <immunology> A group of the d-related HLA antigens (human) found to differ from the dr antigens in genetic locus and therefore inheritance. These antigens are polymorphic glycoproteins comprising alpha and beta chains and are found on lymphoid and other cells, often associated with certain diseases. (12 Dec 1998) |
| HLA-dq antigens | <immunology> A group of the d-related HLA antigens found to differ from the dr antigens in genetic locus and therefore inheritance. These antigens are polymorphic glycoproteins comprising alpha and beta chains and are found on lymphoid and other cells, often associated with certain diseases. (12 Dec 1998) |
| HLA-dr antigens | <immunology> A group of d-related human leukocyte antigens that are polymorphic glycoproteins found on lymphoid cells. They consist of alpha and beta chains and their inheritance differs from that of the dq and dp antigens; their presence seems to be associated with certain skin diseases like pemphigus vulgaris, dermatitis herpetiformis, and type I diabetes. (12 Dec 1998) |
| HTLV-blv antigens | Antigens associated with the HTLV-blv viruses. Htlv-I antigens and HTLV-II antigens belong to this group. (12 Dec 1998) |
Synonyms : CD11 Antigen
Synonyms : CD11a Antigen, Integrin alphaL, Antigen, CD11a, alphaL, Integrin
Synonyms : CD11b Antigen, Mo1 Glycoprotein, alphaM Integrin, Antigen, CD11b, Antigen, Mo1, Integrin, alphaM, alphaM, Integrin
Synonyms : CD11c Antigen, Antigen, CD11c, Antigens, Leu-M5, Leu M5 Antigens, alphaX, Integrin
Synonyms : Alanine Aminopeptidase, Alanyl Aminopeptidase, Amino-oligopeptidase, Aminooligopeptidase, CD13 Antigen, Antigen, CD13, M, Aminopeptidase