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clonal deletion theory The elimination of certain T-cell populations in the thymus that have receptors for self-antigens.
See: immunologic tolerance.
(05 Mar 2000)
point deletion Deletion involving a submicroscopic loss of genetic material too small to be resolved by linkage analysis.
Synonym: nucleotide deletion.
(05 Mar 2000)
sequence deletion Deletion of sequences of bases or amino acids from the genetic material of an individual. Evidence for these deletions may be obtained by cytological methods.
(12 Dec 1998)
nucleotide deletion Deletion of a single nucleotide, which in a transcribed gene will lead to a frameshift mutation.
Synonym: point deletion.
(05 Mar 2000)
deletion <genetics> A chromosome abnormality in which part of a single chromosome has been lost.
(13 Nov 1997)
deletion mutation <molecular biology> A mutation in which one or more (sequential) nucleotides is lost by the genome. If the number lost is not divisible by 3 and is in a coding region, the result is a frameshift mutation.
(18 Nov 1997)
interstitial deletion Deletion that does not involve the terminal parts of a chromosome.
(05 Mar 2000)
terminal deletion Deletion involving the terminal part of a chromosome and leading to a adhesive terminus.
(05 Mar 2000)
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