| ACP | accessory conduction pathway; acid phosphatase; acyl carrier protein; American College of Pathologis... |
|---|---|
| AHI | active hostility index; Animal Health Institute; apnea-plus-hypopnea index |
| AMC | academic medical center; acetylmethyl carbinol; Animal Medical Center; antibody-mediated cytotoxicit... |
| APF | acidulated phosphofluoride; American Psychological Foundation; anabolism-promoting factor; animal pr... |
| APG | acid-precipitated globulin; ambulatory patient group; animal pituitary gonadotropin; antegrade pyelo... |
| Crotalus toxin | <herpetology> The toxin of rattlesnake. (05 Mar 2000) |
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| HC toxin reductase | <enzyme> Nadph-dependent enzyme from maise which inactivates the cyclic tetrapeptide, hc toxin, from cochliobolus carbonum; amino acid sequence given in first source Registry number: EC 1.- Synonym: hm1 gene product (26 Jun 1999) |
| scarlet fever erythrogenic toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |
| Schick test toxin | Corynebacterium diphtheriae toxin diluted so that the inoculated dose (0.1 or 0.2 ml) will contain 1/50 th of guinea pig minimal lethal dose. See: Schick test. Synonym: diagnostic diphtheria toxin. (05 Mar 2000) |
| Shiga like toxin | <protein> Group of structurally related toxins that block eukaryotic protein synthesis by cleaving the 28S rRNA subunit of ribosomes. Examples: Shiga toxin, Shiga like toxins SLT 1 and SLT 2 of Escherichia coli. (18 Nov 1997) |
| Shiga toxin | <protein> Bacterial toxin from Shigella dysenteriae that blocks eukaryotic protein synthesis. See: Shiga like toxins. (18 Nov 1997) |
| streptococcus erythrogenic toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |
| normal toxin | A toxin solution holding exactly 100 lethal doses in 1 ml. (05 Mar 2000) |
| diagnostic diphtheria toxin | Corynebacterium diphtheriae toxin diluted so that the inoculated dose (0.1 or 0.2 ml) will contain 1/50 th of guinea pig minimal lethal dose. See: Schick test. Synonym: diagnostic diphtheria toxin. (05 Mar 2000) |
| Dick test toxin | A culture filtrate of lysogenised group A strains of beta-haemolytic streptococci, erythrogenic when inoculated into the skin of susceptible persons, and neutralised by antibodies that appear during scarlet fever convalescence; three immunological types (A, B, and C) are recognised. Synonym: Dick test toxin, erythrogenic toxin, scarlet fever erythrogenic toxin. (05 Mar 2000) |
| dinoflagellate toxin | A potent neurotoxin that is thought to act similarly to botulinus toxin by impairing the synthesis or the release of acetylcholine. (05 Mar 2000) |
| diphtheria toxin | <protein> An ab exotoxin (62 kD) coded by _ corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP ribosylates elongation factor 2, thereby halting mRNA translation. (18 Nov 1997) |
| intracellular toxin | <protein> Heat stable polysaccharide like toxin bound to a bacterial cell. The term is used more specifically to refer to lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria. There are three parts to the molecule, the Lipid A (six fatty acid chains linked to two glucosamine residues), the core oligosaccharide (branched chain of ten sugars) and a variable length polysaccharide side chain (up to 40 sugar units in smooth forms) that can be removed without affecting the toxicity (rough LPS). Some endotoxin is probably released into the medium and endotoxin is responsible for many of the virulent effects of gram-negative bacteria. (18 Nov 1997) |
| t-2 toxin | <chemical> (3 alpha,4 beta,8 alpha)-12,13-epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-diacetate 8-(3-methylbutanoate). A potent mycotoxin produced in feedstuffs by several species of the genus fusarium. It elicits a severe inflammatory reaction in animals and has teratogenic effects. Chemical name: Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)- (12 Dec 1998) |
| tetanus toxin | <protein> Neurotoxin released by Clostridium tetani, becomes active when peptide cleaved proteolytically to heavy (100 kD) and light (50 kD) chains held together by disulphide bond. Heavy chain binds to disialogangliosides (GD2 and GD1b) and part of the peptide (the amino terminal B fragment) forms a pore: light chain is a zinc endopeptidase that specifically attacks synaptobrevin, to block neurotransmitters. See: botulinum toxin (18 Nov 1997) |