| ACE | Angiotensin Converting Enzyme = Kininase II = Dipeptidyl Carboxypepti... |
|---|---|
| RAA | Renin-Angiotensin-Aldosterone |
| AI, AII, AIII | angiotensin I, II, III |
| ACE | acetonitrile; acetylcholine esterase; acute cerebral encephalopathy; acute coronary event; adrenocor... |
| ACEDS | angiotensin-converting enzyme dysfunction syndrome |
| angiotensin II | <chemical> The active form of angiotensin. An octapeptide found in blood, it is synthesised from angiotensin I and quickly destroyed. Angiotensin II causes profound vasoconstriction with resulting increase in blood pressure. The clinically and experimentally used bovine form has valine in position 5 where the human form has isoleucine. Pharmacological action: vasoconstrictor agents. Chemical name: Angiotensin II (12 Dec 1998) |
|---|---|
| angiotensin III | <chemical> A heptapeptide formed by the enzymatic hydrolysis of angiotensin II. It has greater activity than angiotensin II for stimulating aldosterone synthesis and in the release of prostaglandins but only 20% of the pressor activity. Chemical name: Angiotensin II, 1-de-L-aspartic acid- (12 Dec 1998) |
| angiotensin I (Phe 8-His 9) hydrolase | <enzyme> Cleaves the cooh-terminal dipeptide his(9)-leu(10) from the decapeptide angiotensin i Registry number: EC 3.4.15.- Synonym: atypical angiotensin-converting enzyme (26 Jun 1999) |
| angiotensin precursor | angiotensin |
| angiotensin-related carboxypeptidase | <enzyme> Rat and bovine brain synaptosomal enzyme can hydrolyze angiotensin I to des-leu angiotensin I, but no further Registry number: EC 3.4.- Synonym: angiotensin-specific carboxypeptidase (26 Jun 1999) |
| receptors, angiotensin | Cell surface proteins that bind angiotensins and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
| renin-angiotensin system | <physiology> A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex. (25 Jun 1999) |
| 1-sarcosine-8-isoleucine angiotensin II | <chemical> An angiotensin II analog which acts as a highly specific inhibitor of angiotensin II. Pharmacological action: angiotensin-converting enzyme inhibitors, antihypertensive agents. Chemical name: Angiotensin II, 1-(N-methylglycine)-8-L-isoleucine- (12 Dec 1998) |