| trophoneurotic leprosy | A form of leprosy chiefly affecting the nerves, marked by hyperesthesia succeeded by anaesthesia, and by paralysis, ulceration, and various trophic disturbances, terminating in gangrene and mutilation. Synonym: Danielssen's disease, Danielssen-Boeck disease, dry leprosy, trophoneurotic leprosy. (05 Mar 2000) |
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| tuberculoid leprosy | A benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges. Synonym: nodular leprosy, smooth leprosy. (05 Mar 2000) |
| lazarine leprosy | An acute form occurring in pure diffuse lepromatous leprosy presenting irregularly shaped, intensely erythematous, tender plaques, especially of the legs, with tendency to ulceration and scarring. Synonym: lazarine leprosy, Lucio's leprosy phenomenon. (05 Mar 2000) |
| lepromatous leprosy | A form of leprosy in which nodular cutaneous lesions are infiltrated, have ill-defined borders, and are bacteriologically positive; the lepromin test is negative, i.e., the immunologic mechanism of the patient is not responsive to the Mycobacterium leprae infection. (05 Mar 2000) |
| leprosy | <infectious disease> Caused by Mycobacterium leprae, an obligate intracellular parasite that survives lysosomal enzyme attack by possessing a waxy coat. Leprosy is a chronic disease associated with depressed cellular (but not humoral) immunity, the bacterium requires a lower temperature than 37쵣 and thrives particularly in peripheral Schwann cells and macrophages. Only humans and the nine banded armadillo are susceptible. (18 Nov 1997) |
| leprosy bacillus | A species of gram-positive, aerobic bacteria that causes leprosy in man. Its organisms are generally arranged in clumps, rounded masses, or in groups of bacilli side by side. (12 Dec 1998) |
| leprosy, borderline | A form of leprosy in which there are clinical manifestations of both principal types (lepromatous and tuberculoid). The disease may shift toward one of these two polar or principal forms. (12 Dec 1998) |
| leprosy, lepromatous | A chronic communicable infection which is a principal or polar form of leprosy. This disorder is caused by mycobacterium leprae and produces diffuse granulomatous skin lesions in the form of nodules, macules, or papules. The peripheral nerves are involved symmetrically and neural sequelae occur in the advanced stage. (12 Dec 1998) |
| leprosy test | <investigation> A test for leprosy where an extract of infected tissue (antigen) is injected under the skin to determine if you have a current or recent leprosy infection. Normally, little or no skin reaction should result from the injection. A positive skin reaction indicates a leprosy infection. (27 Sep 1997) |
| leprosy, tuberculoid | A principal or polar form of leprosy in which the skin lesions are few and are sharply demarcated. Peripheral nerve involvement is pronounced and may be severe. Unlike lepromatous leprosy (leprosy, lepromatous), the lepromin test is positive. Tuberculoid leprosy is rarely a source of infection to others. (12 Dec 1998) |
| Lucio's leprosy | An acute form occurring in pure diffuse lepromatous leprosy presenting irregularly shaped, intensely erythematous, tender plaques, especially of the legs, with tendency to ulceration and scarring. Synonym: lazarine leprosy, Lucio's leprosy phenomenon. (05 Mar 2000) |
| Lucio's leprosy phenomenon | An acute form occurring in pure diffuse lepromatous leprosy presenting irregularly shaped, intensely erythematous, tender plaques, especially of the legs, with tendency to ulceration and scarring. Synonym: lazarine leprosy, Lucio's leprosy phenomenon. (05 Mar 2000) |