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hereditary amyloidosis <neurology> A disorder in which various peripheral nerves are infiltrated with amyloid and their functions disturbed, an abnormal prealbumin is also formed and is present in the blood; characteristically, it begins during mid-life and is found largely in persons of Portuguese descent. Other rare clinical types occur.
Inheritance: autosomal dominant.
Synonym: familial amyloidosis, hereditary amyloidosis.
(05 Mar 2000)
secondary amyloidosis Amyloidosis occurring in association with another chronic inflammatory disease; organs chiefly involved are the liver, spleen, and kidneys, and the adrenal glands less frequently.
(05 Mar 2000)
senile amyloidosis A common form of amyloidosis in very old people, usually mild and limited to the heart.
See: amyloidosis of aging.
(05 Mar 2000)
nodular amyloidosis A localised form of amyloidosis in which amyloid occurs as masses or nodules beneath the skin or mucous membranes, e.g., in the larynx.
Synonym: amyloid tumour, focal amyloidosis.
(05 Mar 2000)
familial amyloidosis <neurology> A disorder in which various peripheral nerves are infiltrated with amyloid and their functions disturbed, an abnormal prealbumin is also formed and is present in the blood; characteristically, it begins during mid-life and is found largely in persons of Portuguese descent. Other rare clinical types occur.
Inheritance: autosomal dominant.
Synonym: familial amyloidosis, hereditary amyloidosis.
(05 Mar 2000)
focal amyloidosis A localised form of amyloidosis in which amyloid occurs as masses or nodules beneath the skin or mucous membranes, e.g., in the larynx.
Synonym: amyloid tumour, focal amyloidosis.
(05 Mar 2000)
lichen amyloidosis Localised cutaneous amyloidosis with pruritic brownish-red papules, most commonly on the lower legs, due to amyloid infiltration of the papillary dermis.
Synonym: amyloidosis cutis, lichen amyloidosis.
Origin: G. Leichen, lichen, a lichen-like eruption + eidos, resemblance
(05 Mar 2000)
lichenoid amyloidosis Localised cutaneous amyloidosis with pruritic brownish-red papules, most commonly on the lower legs, due to amyloid infiltration of the papillary dermis.
Synonym: amyloidosis cutis, lichen amyloidosis.
Origin: G. Leichen, lichen, a lichen-like eruption + eidos, resemblance
(05 Mar 2000)
light chain-related amyloidosis A form of primary amyloidosis in which the fibrillar amyloid deposits are derived from the amino terminal variable region of the light chains of immunoglobulin; seen in B-lymphocyte and plasma-cells dyscrasias.
(05 Mar 2000)
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