| AA | 1) Aortic Arch(= Arcus Aortae)(= AA); 대동맥궁 2) Aplastic Anemia - Anemia |
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| AEF | Amyloid Enhancing Factor |
| AH | 1) Atrial Hypertrophy 2) Anti-Hyaluronidase 3) Amyloid imm... |
| AL | Amyloid immunoglobulin Light chain protein |
| AP | 1) Alkaline Phosphatase = ALP 2) Amyloid Plasm... |
| secretory component of IgA | <immunology, protein> A polypeptide chain of about 60 kD that aids secretion of the IgA, a portion of the IgA receptor on the plasmalemma of the inner side of the epithelial cells lining the gut, which is proteolysed when the IgA receptor complex has travelled through the cell after receptor mediated endocytosis at the inner face, to the outer (luminal) face. (18 Nov 1997) |
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| two-component plasma | <radiobiology> Refers to a plasma containing a cool thermal component and a population of high energy particles (such as from neutral beam injection) which are in the process of thermalising (slowing down). (09 Oct 1997) |
| fast component | <molecular biology> A segment of eukaryotic DNA consisting of highly-repeated nucleotide sequences which, when the entire duplex DNA molecule is denatured (the double-stranded helix comes apart and becomes single strands) and then allowed to renature (the complementary single strands come together to form a helix), will be the first segment to renature. (09 Oct 1997) |
| amyloid | Glycoprotein deposited extracellularly in tissues in amyloidosis. The glycoprotein may either derive from light chain of immunoglobulin (AIO (amyloid of immune origin): 5-18 kD glycoprotein, product of a single clone of plasma cells, the N terminal part of lambda or kappa light chain) or, in what used to be referred to as AUO, amyloid of unknown origin, from serum amyloid A (SAA), one of the acute phase proteins that increases many fold in inflammation. The polypeptides are organised as a _ pleated sheet making the material rather inert and insoluble. Minor protein components are also found. Should be distinguished from _ amyloid deposited in the brain and that is derived from amyloid precursor protein (see amyloidogenic glycoprotein. (18 Nov 1997) |
| amyloid A-degrading serine protease | <enzyme> Reduced in amyloidosis associated with rheumatoid arthritis Registry number: EC 3.4.21.- Synonym: amyloid a-degrading activity, aad-protease (26 Jun 1999) |
| amyloid angiopathy | Deposition of acellular hyaline material in small arteries and arterioles of the leptomeninges and cerebral cortex in the elderly with resulting predilection for recurrent lobar intraparenchymal haematomas. (05 Mar 2000) |
| amyloid beta-protein | A 4 kD protein, 39-43 amino acids long, expressed by a gene located on chromosome 21. It is the major protein subunit of the vascular and plaque amyloid filaments in individuals with alzheimer's disease and in aged individuals with trisomy 21 (down syndrome). The protein is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue. (12 Dec 1998) |
| amyloid beta-protein precursor | A precursor to the amyloid-beta protein (beta/a4). Alterations in the expression of the amyloid beta-protein precursor (abpp) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both alzheimer disease and down syndrome. Abpp is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/a4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in alzheimer disease, down syndrome and, to a limited extent, in normal aging. (12 Dec 1998) |
| amyloid bodies of the prostate | An obsolete term for small masses of colloid material often present in the tubules of the gland. See: corpus amylaceum. (05 Mar 2000) |
| amyloid corpuscle | One of a number of small ovoid or rounded, sometimes laminated, bodies resembling a grain of starch and found in nervous tissue, in the prostate, and in pulmonary alveoli; of little pathological significance, and apparently derived from degenerated cells or proteinaceous secretions. Synonym: amniotic corpuscle, amylaceous corpuscle, amyloid corpuscle, colloid corpuscle. (05 Mar 2000) |
| amyloid degeneration | Infiltration of amyloid between cells and fibres of tissues and organs. Synonym: waxy degeneration. (05 Mar 2000) |
| amyloid kidney | A kidney in which amyloidosis has occurred, usually in association with some chronic illness such as multiple myeloma, tuberculosis, osteomyelitis, or other chronic suppurative inflammation; such kidney's are moderately enlarged and grossly manifest a waxy appearance, with amyloid deposited beneath the endothelium in the glomerular loops and in the arterioles, apparently beginning as foci of thickening of the basement membranes. Synonym: waxy kidney. (05 Mar 2000) |
| amyloid nephrosis | The nephrotic syndrome due to deposition of amyloid in the kidney. See: renal amyloidosis. (05 Mar 2000) |
| amyloid neuropathies | Disorders of the peripheral nervous system associated with deposition of amyloid. Amyloid neuropathies may result from non-hereditary or hereditary amyloidosis. Several different forms of familial amyloid neuropathies have been described, most of which have specific mutations in the prealbumin gene. (12 Dec 1998) |
| amyloid precursor protein | <protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients. (04 May 1997) |