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beta-alanine <chemical> Beta-alanine. An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing gaba. A rare genetic disorder, hyper-beta-alaninaemia, has been reported.
Chemical name: beta-Alanine
(12 Dec 1998)
beta-alanine-pyruvate aminotransferase <enzyme> An enzyme that reversibly transfers the amino group of beta-alanine to paruvate, thus producing l-alanine and malonate saemialdehyde. A deficiency of this enzyme is believed to be the cause of hyper-beta-alaninaemia.
(05 Mar 2000)
n-acetylmuramoyl-l-alanine amidase <enzyme> An autolytic enzyme bound to the surface of bacterial cell walls. It catalyses the hydrolysis of the link between n-acetylmuramoyl residues and l-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan.
Chemical name: Peptidoglycan amidohydrolase
Registry number: EC 3.5.1.28
(12 Dec 1998)
D-alanyl-L-alanine endopeptidase <enzyme> Acts on peptidoglycan
Registry number: EC 3.4.99.-
Synonym: d-ala-l-ala endopeptidase
(26 Jun 1999)
enkephalin, leucine-2-alanine <chemical> N-(n-(n-(n-l-tyrosyl-d-alanyl)glycyl)-l-phenylalanyl)-d-leucine. A synthetic delta-selective opioid peptide with analgesic properties. Treatment with dadle results in transient depression of mean arterial blood pressure and heart rate.
Chemical name: D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-
(12 Dec 1998)
UDP-N-acetylmuramoylalanyl-glutamyl-2,6-diaminopimelate-alanyl-alanine ligase <enzyme> Reaction: ATP + udp-n-acetylmuramoyl-l-ala-d-glu-2,6 -diaminoheptanedioate d-ala-d-ala = ADP + orthophosphate + udp-n-acetylmuramoyl-l-ala-d-glu-6-carboxy-l-lys-d-ala-d-ala; 454 amino acids, mw 48 kD; from bacteria; final step in synthesis of udp-n-acetylmuramoyl pentapeptide; genbank x62437
Registry number: EC 6.3.2.15
Synonym: udp-n-acetylmuramoyl-alanyl-d-glutamyl-meso-2,6-diaminopimeloyl-d-alanyl-d-alanine synthetase, murf gene product, udp-n-acetylmuramoyl-l-ala-glu-meso-2,6-diaminopimeloyl-ala-ala synthetase
(26 Jun 1999)
3-chloro-D-alanine hydrogen chloride-lyase <enzyme> Pseudomonas putida enzyme; forms cysteine from 3-chloro-d-alanine and hydrogen sulfide
Registry number: EC 4.5.-
Synonym: cahc-lyase, 3-chloro-d-alanine chloride-lyase (deaminating)
(26 Jun 1999)
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