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slow reacting substance of anaphylaxis <immunology> Potent bronchoconstrictor and inflammatory agent released by mast cells, an important mediator of allergic bronchial asthma.
A mixture of three leukotrienes (LTC4 mainly, LTD4 and LTE4)
(18 Nov 1997)
systemic anaphylaxis The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen).
See: anaphylactic shock.
Synonym: systemic anaphylaxis.
(05 Mar 2000)
inverse anaphylaxis Anaphylactic shock in an animal (e.g., guinea pig) whose tissues contain Forssman antigen, resulting from an intravenous injection of serum that contains Forssman's antibody.
(05 Mar 2000)
eosinophil chemotactic factor of anaphylaxis A peptide (MW 500 to 600) that is chemotactic for eosinophilic leukocytes and is released from disrupted mast cells.
(05 Mar 2000)
local anaphylaxis The immediate, transient kind of response that follows the injection of antigen (allergen) into the skin of a sensitised individual and is limited to the area surrounding the site of inoculation.
See: skin test.
(05 Mar 2000)
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