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adhesion phenomenon A phenomenon manifested by the adherence of antigen-antibody-complement complex to "indicator cells" (microorganisms, platelets, leukocytes, or erythrocytes), the reaction being sensitive and specific for the antigen and antibody in the complex.
Synonym: erythrocyte adherence phenomenon, immune adherence phenomenon, red cell adherence phenomenon.
(05 Mar 2000)
adhesion-related kinase <chemical> New member of the immunoglobulin superfamily with 2 immunoglobulin-like domains
Synonym: ark protein, ark receptor tyrosine kinase
(26 Jun 1999)
adhesion structures linked tyrosine kinase <enzyme> Isolated from mouse embryonic stem cells
Registry number: EC 2.7.1.-
Synonym: hyk protein
(26 Jun 1999)
adhesion test The diagnostic application of the immune adhesion phenomenon.
Synonym: erythrocyte adherence test, immune adhesion test, red cell adherence test.
(05 Mar 2000)
bacterial adhesion Physicochemical property of fimbriated (fimbriae, bacterial) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
(12 Dec 1998)
receptors, leukocyte-adhesion Family of proteins associated with the capacity of leukocytes, including lymphocytes, monocytes, and neutrophils, to adhere to each other and to certain substrata, e.g., the c3bi component of complement. Members of this family are the lymphocyte function-associated antigen-1 (lfa-1), the macrophage-1 antigen (mac-1), and the antigen p150,95 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited leukocyte-adhesion deficiency syndrome, which is characterised by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
(12 Dec 1998)
cell adhesion See: adhesins, cadherins, cell adhesion molecules (CAMs), contact sites A, DLVO theory, integrins, sorting out, uvomorulin and various specialised junctions (adherens junctions, desmosomes, focal adhesions, gap junction and zonula occludens).
(18 Nov 1997)
cell adhesion kinase <enzyme> From hela cells; involved in cell-cell interactions; genbank l20817
Registry number: EC 2.7.1.-
Synonym: cak protein
(26 Jun 1999)
cell adhesion molecules Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.
(12 Dec 1998)
cell adhesion molecules, neuronal Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with ncam (neural cell adhesion molecule), now known to be expressed in a variety of tissues and cell types in addition to nervous tissue.
(12 Dec 1998)
cell adhesion molecules, neuron-glia Cell adhesion molecules that mediate neuron-neuron adhesion and neuron-astrocyte adhesion. They are expressed on neurons and schwann cells, but not astrocytes and are involved in neuronal migration, neurite fasciculation, and outgrowth. Ng-cam is immunologically and structurally distinct from ncam (neural cell adhesion molecules).
(12 Dec 1998)
water of adhesion Water held by molecular attraction in contact with solid surfaces, but not forming an essential part of their constitution.
(05 Mar 2000)
primary adhesion Healing by fibrous adhesion, without suppuration or granulation tissue formation.
Synonym: primary adhesion, primary union.
(05 Mar 2000)
secondary adhesion Delayed closure of two granulating surfaces.
Synonym: secondary adhesion, secondary union.
(05 Mar 2000)
differential adhesion The differential adhesion hypothesis was advanced by Steinberg to explain the mechanism by which heterotypic cells in mixed aggregates sort out into isotypic territories. Quantitative differences in homo and hetero typic adhesion are supposed to be sufficient to account for the phenomenon without the need to postulate cell type specific adhesion systems: fairly generally accepted, although some tissue specific cell adhesion molecules are now known to exist.
(18 Nov 1997)
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