| inosine monophosphate | <chemical> Inosine 5'-monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Chemical name: 5'-Inosinic acid (12 Dec 1998) |
|---|---|
| orotidine 5'-monophosphate | Orotidine 5'-monophosphate;an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acids. Synonym: orotidine 5'-monophosphate. (05 Mar 2000) |
| terpenyl monophosphate hydrolase | <enzyme> Hydrolyzes bornyl phosphate to borneol Registry number: EC 3.1.3.- (26 Jun 1999) |
| thiamine monophosphate | <chemical> Thiamine dihydrogen phosphate ester. The monophosphate ester of thiamine. Synonym: monophosphothiamine; vitamin b1 monophosphate. Chemical name: Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(2-(phosphonooxy)ethyl)-, chloride (12 Dec 1998) |
| thymidine 5'-monophosphate | A major constituent of DNA. Synonym: thymidine 5'-monophosphate, thymine nucleotide. (05 Mar 2000) |
| thymidine monophosphate | <chemical> 5-thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. Chemical name: 5'-Thymidylic acid (12 Dec 1998) |
| uridine 5'-monophosphate | Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. Synonym: UMP synthase, uridine 5'-monophosphate. Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria. (05 Mar 2000) |
| uridine 5'-monophosphate synthase | <chemical> Consists of orotate phosphoribosyltransferase EC 2.4.2.10 and orotidylate decarboxylase EC 4.1.1.23 Chemical name: synthase, uridylate Synonym: ump synthase, uridine 5'-phosphate synthase, uridylate synthase (26 Jun 1999) |
| uridine monophosphate | <chemical> 5'-uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Chemical name: 5'-Uridylic acid (12 Dec 1998) |
| uridine monophosphate kinase | <enzyme> Catalyses the phosphorylation of ump to udp; an aspect of EC 2.7.4.4 Registry number: EC 2.7.4.- Synonym: ump kinase, uridine-5-monophosphate kinase, uridylate kinase (26 Jun 1999) |
| 5-methyldeoxycytidine monophosphate aminohydrolase | <enzyme> Forms thymidylate; does not act on dcmp Registry number: EC 3.5.4.- Synonym: 5mdcmp aminohydrolase (26 Jun 1999) |
| adenosine | <biochemistry> A ribonucleotide which consists of the nitrogenous base adenine linked to the sugar ribose. <drug> A cardiac drug used in terminating PSVT involving reentry pathways that include the AV node or Wolff-Parkinson-White syndrome. For atrial flutter, atrial fibrillation, atrial or ventricular tachycardias, adenosine may produce transient AV block that may help identify the rhythm. Pharmacologic action: Endogenous purine nucleoside that depresses AV node and sinus node activity. Brief duration of action (1-2 min). Dose: Rapid 6 mg IV bolus over 1-3 sec. May repeat at 12 mg IV bolus within 1-2 min Patients taking theophylline may require larger doses. Use a smaller dose with cardiac transplant patients. Potential complications: Common but transient - flushing, dyspnea, chest pain, bradycardia, and ventricular ectopy. Theophylline (and caffeine) blocks adenosine's effects. Dipyridamole potentiates adenosine's effects. Use other agents to avoid these drug interactions. (15 Mar 2000) |
| adenosine 3',5'-cyclic phosphate phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
| adenosine 3'-phosphate | 3'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine 3'-phosphate 5'-phosphosulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |