| adenocarcinoma, clear cell | An adenocarcinoma characterised by the presence of varying combinations of clear and hobnail-shaped tumour cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumours, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (12 Dec 1998) |
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| adenocarcinoma, follicular | An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (12 Dec 1998) |
| adenocarcinoma in Barrett's oesophagus | An adenocarcinoma arising in the lower third of the oesophagus that has become columnar cell lined (Barrett's mucosa) due to gastroesophageal reflux. (05 Mar 2000) |
| adenocarcinoma in situ | A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma; reported in the endometrium, large intestine, cervix, and other sites. (05 Mar 2000) |
| adenocarcinoma, mucinous | An adenocarcinoma producing mucin in significant amounts. (12 Dec 1998) |
| adenocarcinoma, papillary | An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (12 Dec 1998) |
| adenocarcinoma, scirrhous | An adenocarcinoma with a hard (greek skirrhos, hard) structure owing to the formation of dense connective tissue in the stroma. (12 Dec 1998) |
| alveolar adenocarcinoma | <tumour> Adenocarcinoma of the lung in which tumour cells form structures resembling alveoli. (05 Mar 2000) |
| bronchiolar adenocarcinoma | <tumour> A carcinoma, thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli; involvement may be uniformly diffuse and massive, or nodular, or lobular; microscopically, the neoplastic cells are cuboidal or columnar and form papillary structures; mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells; metastases in regional lymph nodes, and even in more distant sites, are known to occur, but are infrequent. Synonym: alveolar cell carcinoma, bronchiolar adenocarcinoma, bronchiolo-alveolar carcinoma, bronchioloalveolar adenocarcinoma. (05 Mar 2000) |
| bronchioloalveolar adenocarcinoma | <tumour> A carcinoma, thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli; involvement may be uniformly diffuse and massive, or nodular, or lobular; microscopically, the neoplastic cells are cuboidal or columnar and form papillary structures; mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells; metastases in regional lymph nodes, and even in more distant sites, are known to occur, but are infrequent. Synonym: alveolar cell carcinoma, bronchiolar adenocarcinoma, bronchiolo-alveolar carcinoma, bronchioloalveolar adenocarcinoma. (05 Mar 2000) |
| pancreatic adenocarcinoma | <radiology> Males (60%), blacks more than whites, risk factors: tobacco, familial pancreatitis, not EtOH!, focal mass in 95%, pancreatic head in 66%, small (low-density, hypoechoic) mass, infiltrates locally, obstructs ducts and encases vessels, metastasis to liver, local nodes See also: pancreatic neoplasms (12 Dec 1998) |
| papillary adenocarcinoma | <tumour> An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles; occurs most frequently in the ovary and thyroid gland. (05 Mar 2000) |
| renal adenocarcinoma | <radiology> Hypernephroma, renal cell carcinoma, arises from proximal collecting tubule, 10% bilateral adenocarcinoma types: papillary, alveolar, onchocytoma vascularity, 85% hypervascular (require pre-op embolization), 10% hypovascular (usually papillary type), 5% avascular associated with: tuberous sclerosis, von Hippel-Lindau syndrome see also: staging (12 Dec 1998) |
| renal adenocarcinoma: staging | <radiology> Typical presentation: Haematuria . . . . . 70% Fever . . . . . . . 16% Pain . . . . . . . . 50% Polycythemia . . . . 3% Palpable mass . . . 20% Anatomic staging (TNM): T1 Small tumour, kidney not enlarged T2 Large tumour, contained within renal capsule T3 Extension into perinephric fat or renal vein T4 Invasion of adjacent organs (12 Dec 1998) |
| renal adenocarcinoma: vascularity | <radiology> 85% hypervascular (require pre-op embolization), 10% hypovascular (usually the papillary type), 5% avascular also: 10% are bilateral (12 Dec 1998) |