| platelet-activating factor | <cytokine> Potent phospholipid activator and mediator of many leucocyte functions, including platelet aggregation, inflammation, and anaphylaxis. It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction. Synonym: platelet-aggregating factor. Acronym: PAF (20 Sep 2002) |
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| connective tissue activating peptide III | Cytokine, produced from platelet basic protein, that acts as a growth factor. (18 Nov 1997) |
| neutrophil activating factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| neutrophil activating protein | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| insulin activating factor | <chemical> Activates insulin gene transcription in pancreatic beta cells. Synonym: insaf (05 Dec 1998) |
| osteoclast activating factor | A lymphokine that stimulates bone resorption and inhibits bone-collagen synthesis. (05 Mar 2000) |
| JNK-activating protein kinase | <enzyme> A dual specificity kinase that activates jun kinases and p38-mpk2; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: jnk kinase, jnkk, hemipterous protein, hep protein, jun amino-terminal kinase kinase, jn kinase kinase, hep gene product (26 Jun 1999) |
| acetoacetyl-acyl carrier protein synthase | <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin Registry number: EC 2.3.1.- Synonym: acetoacetyl-acp synthase (26 Jun 1999) |
| acyl | An organic radical derived from an organic acid by the removal of the carboxylic hydroxyl group. (05 Mar 2000) |
| acyl-ACP dehydrogenase | enoyl-ACP reductase (NADPH) |
| acyl carrier protein | <protein> A small (77 peptides long) protein which binds six other enzymes involved in fatty acid synthesis. It was first isolated in E. Coli bacteria. (09 Oct 1997) |
| acyl carrier protein acylase | <enzyme> From E coli Registry number: EC 2.3.1.- Synonym: acp acylase (26 Jun 1999) |
| acyl-CoA | RCH2COSCoA or RCH2CO~SCoA;condensation product of a carboxylic acid and coenzyme A, and metabolic intermediate of importance, notably in the oxidation and synthesis of fat. Synonym: acyl-coenzyme A. (05 Mar 2000) |
| acyl-CoA-1-O-alkyl-2-acetyl-sn-glycerol acyltransferase | <enzyme> From hl-60 cells; related to platelet-activating factor metabolism Registry number: EC 2.3.1.- Synonym: acyl-CoA-1-o-hexadecyl-2-acetyl-sn-glycerol acyltransferase, acaag-acyltransferase, acyl-coenzyme a-1-o-alkyl-2-acetyl-sn-glycerol acyltransferase (26 Jun 1999) |
| acyl-CoA-6-aminopenicillanic acid acyltransferase | <enzyme> Acyl CoA and aminopenicillanic acid yield penicillin and CoA Registry number: EC 2.3.1.- Synonym: 6-apa acyltransferase, 6-aminopenicillanic acid-phenacetyl-CoA-phenoxyacetyl-CoA transferase, acyl-coenzyme a-6-aminopenicillanic acid acyltransferase, isopenicillin n-phenylacetyl-CoA acyltransferase, penicillin acyltransferase, isopenicillin n-phenylacetyl-coenzyme a acyltransferase, acyl-CoA-ipn acyltransferase, isopenicillin n acyltransferase, aat gene product, pende gene product (26 Jun 1999) |