| CALLA | Common Acute Lymphocytic(Lymphoblastic) Leukemia Antigen = CD10 = Enk... |
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| cALLA | common acute lymphoblastic leukemia antigen |
| LALL | lymphomatous acute lymphoblastic leukemia |
| TALL, T-ALL | T-cell acute lymphoblastic leukemia |
| TALLA | T-cell acute lymphoblastic leukemia antigen |
| leukaemia, megakaryocytic, acute | Nonlymphocytic leukaemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. Myelofibrosis or increased bone marrow reticulin is common. (12 Dec 1998) |
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| leukaemia, myelocytic, acute | Progressive, malignant disease of the myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate. (12 Dec 1998) |
| leukaemia, nonlymphocytic, acute | Acute leukaemia distinguished from acute lymphocytic leukaemia (all) by the morphology of the marrow and blood leukaemic cells. Cytoplasmic granules are usually present and the nucleus is usually large and irregular. Anll is more common in adults than all and occurs at any age. (12 Dec 1998) |
| abelson leukaemia virus | A defective murine leukaemia virus capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukaemia after superinfection with friend, moloney, or rauscher virus. (12 Dec 1998) |
| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| adult T-cell leukaemia | Lymph nodes show a mixture of small and large atypical cells which are polymorphic and express nuclear pleiomorphism. Adult T-cell leukaemia is caused by HTLV-1 and is rare in the US and Europe but common in Japan. Tumour cells express CD2, CD3, CD5 and lack CD7. The most common chromosome change reported in adult T-cell leukaemia is presence of the 14q + marker (05 Mar 2000) |
| aleukaemic leukaemia | Leukaemia in which abnormal (or leukaemic) cells are absent in the peripheral blood. (05 Mar 2000) |
| avian leukaemia-sarcoma complex | A term applied to a group of transmissible virus-induced diseases of chickens causing sarcoma, myeloblastosis, erythroblastosis, leukosis, osteopetrosis, and lymphomatosis. These agents are closely related viruses (avian leukosis-sarcoma virus) causing prolferation of immature erythroid, myeloid, or lymphoid cells, a division of the RNA tumour viruses (subfamily Oncovirinae) causing the avian leukosis-sarcoma complex of diseases; the viruses are subgrouped according to antigenic characteristics and growth in defined types of tissue culture cells. Synonym: avian erythroblastosis virus, avian leukosis-sarcoma virus, avian lymphomatosis virus, avian myeloblastosis virus, avian sarcoma virus, fowl erythroblastosis virus, fowl lymphomatosis virus, fowl myeloblastosis virus. (05 Mar 2000) |
| avian leukaemia virus | <virology> Group of C type RNA tumour viruses (Oncovirinae) that cause various leukaemias and other tumours in birds. The acute leukaemia viruses, that are replication defective and require helper viruses, include avian erythroblastosis (AEV), myeloblastosis (AMV) and myelo cytomatosis viruses. AEV carries two transforming genes, v erbA and v erbB, the cellular homologue of the latter is the structural gene for the epidermal growth factor receptor. AMV carries v myb and causes a myeloid leukaemia, avian myelocytomatosis virus carries v myc. The avian lymphatic leukaemia viruses (ALV) are also Retroviridae but are replication competent and induce neoplasia only after several months, they often occur in conjunction with replication defective leukaemia viruses. (02 Jan 1998) |
| basophilic leukaemia | A form of granulocytic leukaemia in which there are unusually great numbers of basophilic granulocytes in the tissues and circulating blood; in some instances, the immature and mature basophilic forms may represent from 40 to 80% of the total numbers of white blood cells. Synonym: mast cell leukaemia. (05 Mar 2000) |
| B-cell leukaemia | A test which detects the presence of antigens on the surface of B lymphocytes. These antigens can indicate the presence of leukaemia. most often this is used to detect and differentiate chronic lymphocytic leukaemia from acute lymphocytic leukaemia. Origin: Gr. Haima = blood (27 Sep 1997) |
| bovine leukaemia | A lymphoid neoplastic disease in cattle caused by the bovine leukaemia virus. Enzootic bovine leukosis may take the form of lymphosarcoma, malignant lymphoma, or leukaemia but the presence of malignant cells in the blood is not a consistent finding. (12 Dec 1998) |
| bovine leukaemia virus | A type C retrovirus in the subfamily Retrovirinae, commonly infecting cattle, especially dairy cows; in a small proportion of infected cattle, it will cause enzootic bovine leukosis. Synonym: bovine leukosis virus. (05 Mar 2000) |
| cancer, leukaemia | Leukaemia is a cancer of the white blood cells. Leukaemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected. People with leukaemia are at significantly increased risk for developing infections, anaemia, and bleeding. Diagnosis of leukaemia is supported by findings of the medical history and examination, and examining blood under a microscope. Leukaemia cells can be detected and further classified with a bone marrow aspiration and/or biopsy. most patients with leukaemia are treated with chemotherapy. Some patients also may have radiation therapy and/or bone marrow transplantation. (12 Dec 1998) |