| chemotactic factors, macrophage | Cytotaxins liberated from normal or invading cells that specifically attract macrophages. They may be lymphokines, products of antigen, antibody and complement interactions or other. (12 Dec 1998) |
|---|---|
| granulocyte-macrophage colony-stimulating factor | <growth factor, haematology, oncology> An acidic glycoprotein of mw 23 kD with internal disulfide bonds. It is produced in response to a number of inflammatory mediators by mesenchymal cells present in the haemopoietic environment and at peripheral sites of inflammation. It stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from foetal liver progenitor cells. It also has some functional activities in mature granulocytes and macrophages. It is used to promote the recovery of the white blood cells following chemotherapy. Chemical name: Colony-stimulating factor 2 See: colony-stimulating factor. Acronym: GM-CSF (12 Dec 1998) |
| wandering macrophage | <haematology> A macrophage that leaves the blood and migrates to infected tissue. (09 Oct 1997) |
| Hansemann macrophage | Large histiocytes with abundant cytoplasm that may contain Michaelis-Gutmann bodies and one or several nuclei; described in lesions of malacoplakia. (05 Mar 2000) |
| inflammatory macrophage | A macrophage found at sites of inflammation. (05 Mar 2000) |
| fixed macrophage | A relatively immotile macrophage found in connective tissue, lymph nodes, spleen, and bone marrow. Synonym: resting wandering cell. (05 Mar 2000) |
| free macrophage | An actively motile macrophage typically found in sites of inflammation. (05 Mar 2000) |
| activated acetaldehyde | The activated form of acetaldehyde that is formed during the decarboxylation of active pyruvate. Formed in alcohol fermentation and in carbohydrate metabolism. Synonym: a-hydroxyethylthiamin pyrophosphate. (05 Mar 2000) |
| activated amino acid | The product formed by the condensation of the acyl radical of an amino acid and adenosine 5'-monophosphate (originally in the form of adenosine 5'-triphosphate, with elimination of a pyrophosphoric group). Formed in the first step of protein biosynthesis. Synonym: activated amino acid. (05 Mar 2000) |
| activated atom | An atom possessing more than normal energy as a result of input of energy. See: excited state. Synonym: excited atom. (05 Mar 2000) |
| activated carboxylic acid | Derivative of a carboxyl group that is more susceptible to nucleophilic attack than a free carboxyl group; e.g., acid anhydrides, thioesters. (05 Mar 2000) |
| activated charcoal | <drug> A type of carbon produced through exposing a source material such as wood or bone to very high temperatures in the presence of steam, air or carbon monoxide. Activated carbon is very good at removing (adsorbing) contaminants and is used in water filters, to decolour solutions and is sometimes administered to poisoning victims. (15 Jan 1998) |
| activated choline | An intermediate in the formation of phosphatidylcholine (lecithin); formed by the action of cytidine 5'-triphosphate on phosphocholine, linking the choline phosphate group to the alpha-phosphate of the cytidine 5'-triphosphate to give a pyrophosphate. Synonym: activated choline, cytidine diphosphate choline. (05 Mar 2000) |
| activated clotting time | The most common test used for coagulation time in cardiovascular surgery. (05 Mar 2000) |
| activated complex | <chemistry> State of highest energy during a reaction. When reactants form the activated complex, bond breaking and bond formation is occurring. Synonym: transition state. (09 Jan 1998) |