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  • terminal filament
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  • thick filament
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  • thick filament
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  • thin filament
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  • tungsten filament lamp
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IF idiopathic fibroplasia; idiopathic flushing; immersion foot; immunofluorescence; indirect fluorescen...
IFP inflammatory fibroid polyp; insulin, compound F [hydrocortisone], prolactin; intermediate filament p...
IMF idiopathic myelofibrosis; immunofluorescence; intermaxillary fixation; intermediate filament
PHF paired helical filament; personal hygiene facility
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IFP intermediate filament protein
GFP glia filament protein
IMF intermediate filament
KIF keratin intermediate filament
A F-actin
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intermediate filament <cell biology> A class of cytoplasmic filaments of animal cells so named originally because their diameter (nominally 10 nm) in muscle cells was intermediate between thick and thin filaments. Unlike microfilaments and microtubules, the protein sub units of intermediate filaments show considerable diversity and tissue specificity.
See: cytokeratins, desmin, glial fibrillary acidic protein, neurofilament proteins, nestin and vimentin
(18 Nov 1997)
intermediate filament proteins Filaments 7-11 nm in diameter found in the cytoplasm of all cells. Many specific proteins belong to this group, e.g., desmin, vimentin, prekeratin, decamin, skeletin, neurofilin, neurofilament protein, and glial fibrillary acid protein.
(12 Dec 1998)
thick filament <cell biology> Bipolar myosin II filaments (12-14nm diameter, 1.6m long) found in striated muscle.
Myosin filaments elsewhere are often referred to as thick filaments, although their length may be considerably less. The myosin heads project from the thick filament in a regular fashion. There is a central bare zone without projecting heads, the core being formed from antiparallel arrays of LMM regions of the myosin heavy chains. Thick filaments will self assemble in vitro under the right ionic conditions.
(18 Nov 1997)
thin filament Filaments 7-9nm diameter attached to the Z discs of striated muscle, have opposite polarity in each half sarcomere. Built of F actin with associated tropomyosin and troponin.
(18 Nov 1997)
Z filament The thin zig-zag structure at the Z line of striated muscle fibres to which the actin filament's attach.
(05 Mar 2000)
filament See: thick filaments, thin filaments, intermediate filaments and microfilaments.
(18 Nov 1997)
filament-nonfilament count A differential count of the number of neutrophils showing nuclear division and those showing no such division.
(05 Mar 2000)
filament polymorphonuclear leukocyte Any mature polymorphonuclear leukocyte, especially a neutrophilic leukocyte, in which the lobes of the nucleus are interconnected with a thin strand or filament of chromatin.
(05 Mar 2000)
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