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MPNST Malignant Peripheral Nerve Sheath Tumour
rTNF Recombinant human tumour necrosis factor
rhTNF Recombinant human tumour necrosis factor
rhTNF-alpha Recombinant human tumour necrosis factor-alpha
TNF alpha Tumour Necrosis Factor alpha
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antigens, viral, tumour Those proteins recognised by antibodies from serum of animals bearing tumours induced by viruses; these proteins are presumably coded for by the nucleic acids of the same viruses that caused the neoplastic transformation.
(12 Dec 1998)
aortic body tumour Aortic body, carotid body, chemoreceptor, or glomus jugulare tumour; nonchromaffin paraganglioma; receptoma; a relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the carotid body, glomus jugulare, and aortic bodies; consisting histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels.
Compare: paraganglioma.
Synonym: aortic body tumour, carotid body tumour, chemoreceptor tumour, glomus jugulare tumour, nonchromaffin paraganglioma.
Origin: chemo-+ G. Dektes, receiver, fr. Dechomai, to receive, + -oma, tumour
(05 Mar 2000)
ascites tumour <oncology> Tumour that grows in the peritoneal cavity as a suspension of cells.
Obviously such cells have lost anchorage dependence and they can easily be isolated and passaged. Hybridomas are sometimes grown as ascites tumours and the ascites fluid can then be used as the crude antiserum.
(18 Nov 1997)
ascitic tumour <oncology> A tumour of the abdominal cavity which often causes oedema in that cavity.
(09 Oct 1997)
Bednar tumour An uncommon variant of dermatofibrosarcoma protuberans containing heavily pigmented dendritic melanocytes scattered between spindle cells of the tumour.
Synonym: Bednar tumour, storiform neurofibroma.
(05 Mar 2000)
benign nasal tumour A benign tumour of the posterior nasopharynx that is most common in adolescent boys.
Symptoms repeated epistaxis, nasal congestion, nasal discharge and hearing loss. A skull X-ray or a CT scan of the head can confirm the presence of an angiofibroma. Treatment may include the surgical removal of the lesion if it is enlarging or blocking the airway.
(27 Sep 1997)
benign tumour <oncology> A nonmalignant clone of neoplastic cells that does not invade locally or spread to other parts of the body (metastasise), having lost growth control but not positional control. Usually surrounded by a fibrous capsule of compressed tissue.
(29 Sep 1997)
blood tumour Term sometimes used to denote an aneurysm, haemorrhagic cyst, or haematoma.
(05 Mar 2000)
bone tumour <oncology> A general term that includes both malignant growths (cancer) and benign growths in bone.
most cancer in bone tissue is secondary to spread (metastasis) from a distant primary cancer (for example prostate cancer). Primary bone cancer (for example osteogenic sarcoma) or cancer that arises from the bone cells, is relatively rare.
(27 Sep 1997)
borderline tumour A neoplasm of the ovary, usually arising in young women, composed of complex epithelial hyperplasia without stromas invasion; may recur if incompletely removed surgically, but is clinically less aggressive than carcinoma.
Synonym: low malignant potential tumour.
(05 Mar 2000)
brain tumour <oncology, tumour> May be subdivided into primary brain tumours and the more common, secondary brain tumours.
Primary brain tumours (for example astrocytoma, craniopharyngioma, glioma, ependymoma, neuroglioma, oligodendroglioma, glioblastoma multiforme, meningioma, medulloblastoma) arise from the uncontrolled proliferation of cells within the brain.
Secondary brain tumours occur from the spread of cancer into the brain from a distant cancerous organ (metastasis).
Common symptoms of a brain tumour include headache, nausea, vomiting, seizures, change in mentation, neurologic symptoms and loss of memory.
(17 Dec 1997)
brain tumour calcifications <radiology> Oligodendroglioma (90%), craniopharyngioma (70%), ependymoma (60%), choroid plexus papilloma (25%), low-grade astrocytoma (20%), meningioma (10%), others, dermoid, pineal tumours, lipoma, caveat: a calcified intraparenchymal tumour is most likely to be an astrocytoma due to higher overall incidence relative to other tumours mentioned above. Source: Duke review manual
(12 Dec 1998)
brenner tumour A tumour of the ovary whose structure consists of groups of epithelial cells lying in a fibrous connective tissue stroma. Brenner tumours are uncommon, representing less than 1% of all ovarian neoplasms. Malignant brenner tumours are unilateral. Brenner tumours are ordinarily found incidentally in ovaries removed for other reasons, especially in postmenopausal women.
(12 Dec 1998)
Brooke's tumour <tumour> Multiple small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts; frequent autosomal dominant inheritance.
Synonym: acanthoma adenoides cysticum, Brooke's tumour, epithelioma adenoides cysticum, hereditary multiple trichoepithelioma.
Origin: tricho-+ epithelioma
(05 Mar 2000)
brown tumour A mass of fibrous tissue containing haemosiderin-pigmented macrophages and multinucleated giant cells, replacing and expanding part of a bone in primary hyperparathyroidism.
(05 Mar 2000)
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