| RAR | rapidly adapting receptor; rat insulin receptor; retinoic acid receptor; right arm reclining; right ... |
|---|---|
| CDK | cell division kinase; climatic droplet keratopathy; cyclin-dependent kinase |
| PK | penetrating keratoplasty; pericardial knock; pharmacokinetics; pig kidney; Prausnitz-Kustner [reacti... |
| PNK | polynucleotide kinase; pyridoxine kinase |
| RK | rabbit kidney; radial keratotomy; reductase kinase; rhodopsin kinase; right kidney |
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
|---|---|
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| epidermal growth factor receptor protein-tyrosine kinase | <enzyme> The catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of epidermal growth factor receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| fibroblast growth factor receptor-like embryonic kinase | <enzyme> Found in avian embryonic tissue; involved in early differentiation of skeletal muscle. Registry number: EC 2.7.1.- Synonym: frek (26 Jun 1999) |
| light-repressible receptor protein kinase | <enzyme> Photo-regulated protein isolated from arabidopsis thaliana; genbank x97774 Registry number: EC 2.7.1.- Synonym: lrrpk gene product (26 Jun 1999) |
| acral lentiginous melanoma | <tumour> A form of malignant lentigo melanoma that occurs in acral areas not excessively exposed to sunlight and where hair follicles are absent. (05 Mar 2000) |
| amelanotic melanoma | <tumour> An anaplastic melanoma consisting of cells derived from melanocytes but not forming melanin. (05 Mar 2000) |
| benign juvenile melanoma | A benign, slightly pigmented or red superficial small skin tumour composed of spindle-shaped, epithelioid, and multinucleated cells that may appear atypical; most common in children, but also appearing in adults. Synonym: benign juvenile melanoma, epithelioid cell nevus, spindle cell nevus. (05 Mar 2000) |
| cancer, malignant melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. Melanoma can be cured if detected early, before spread (metastasis) to other areas of the body. Diagnosis is confirmed with a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| cancer, melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. It can be cured if detected early, before spread (metastasis) to other areas. Diagnosis is confirmed by a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| malignant lentigo melanoma | <tumour> A melanoma arising from a malignant lentigo. (05 Mar 2000) |
| malignant melanoma | <oncology, tumour> A malignant tumour which arises from the pigment producing cells (melanosomes) of the deeper layers of the skin (or the eye). Melanoma is the leading cause of death attributable to skin lesions. Described as an irregular dark skin lesion that may have areas of varying colour. Often greater than 6 mm in diameter. (27 Sep 1997) |
| malignant melanoma: gallium imaging | <radiology> Greater than50% sensitivity for primary and metastatic sites: 73% sensitivity if lesion is greater than 2 cm, 17% sensitivity if less than 2 cm, see: gallium: indications malignant melanoma (12 Dec 1998) |
| malignant melanoma in situ | A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of malignant melanoma in situ. (05 Mar 2000) |