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MPNST Malignant Peripheral Nerve Sheath Tumour
rTNF Recombinant human tumour necrosis factor
rhTNF Recombinant human tumour necrosis factor
rhTNF-alpha Recombinant human tumour necrosis factor-alpha
TNF alpha Tumour Necrosis Factor alpha
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ascitic tumour <oncology> A tumour of the abdominal cavity which often causes oedema in that cavity.
(09 Oct 1997)
Bednar tumour An uncommon variant of dermatofibrosarcoma protuberans containing heavily pigmented dendritic melanocytes scattered between spindle cells of the tumour.
Synonym: Bednar tumour, storiform neurofibroma.
(05 Mar 2000)
benign nasal tumour A benign tumour of the posterior nasopharynx that is most common in adolescent boys.
Symptoms repeated epistaxis, nasal congestion, nasal discharge and hearing loss. A skull X-ray or a CT scan of the head can confirm the presence of an angiofibroma. Treatment may include the surgical removal of the lesion if it is enlarging or blocking the airway.
(27 Sep 1997)
benign tumour <oncology> A nonmalignant clone of neoplastic cells that does not invade locally or spread to other parts of the body (metastasise), having lost growth control but not positional control. Usually surrounded by a fibrous capsule of compressed tissue.
(29 Sep 1997)
blood tumour Term sometimes used to denote an aneurysm, haemorrhagic cyst, or haematoma.
(05 Mar 2000)
bone tumour <oncology> A general term that includes both malignant growths (cancer) and benign growths in bone.
most cancer in bone tissue is secondary to spread (metastasis) from a distant primary cancer (for example prostate cancer). Primary bone cancer (for example osteogenic sarcoma) or cancer that arises from the bone cells, is relatively rare.
(27 Sep 1997)
borderline tumour A neoplasm of the ovary, usually arising in young women, composed of complex epithelial hyperplasia without stromas invasion; may recur if incompletely removed surgically, but is clinically less aggressive than carcinoma.
Synonym: low malignant potential tumour.
(05 Mar 2000)
brain tumour <oncology, tumour> May be subdivided into primary brain tumours and the more common, secondary brain tumours.
Primary brain tumours (for example astrocytoma, craniopharyngioma, glioma, ependymoma, neuroglioma, oligodendroglioma, glioblastoma multiforme, meningioma, medulloblastoma) arise from the uncontrolled proliferation of cells within the brain.
Secondary brain tumours occur from the spread of cancer into the brain from a distant cancerous organ (metastasis).
Common symptoms of a brain tumour include headache, nausea, vomiting, seizures, change in mentation, neurologic symptoms and loss of memory.
(17 Dec 1997)
brain tumour calcifications <radiology> Oligodendroglioma (90%), craniopharyngioma (70%), ependymoma (60%), choroid plexus papilloma (25%), low-grade astrocytoma (20%), meningioma (10%), others, dermoid, pineal tumours, lipoma, caveat: a calcified intraparenchymal tumour is most likely to be an astrocytoma due to higher overall incidence relative to other tumours mentioned above. Source: Duke review manual
(12 Dec 1998)
brenner tumour A tumour of the ovary whose structure consists of groups of epithelial cells lying in a fibrous connective tissue stroma. Brenner tumours are uncommon, representing less than 1% of all ovarian neoplasms. Malignant brenner tumours are unilateral. Brenner tumours are ordinarily found incidentally in ovaries removed for other reasons, especially in postmenopausal women.
(12 Dec 1998)
Brooke's tumour <tumour> Multiple small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts; frequent autosomal dominant inheritance.
Synonym: acanthoma adenoides cysticum, Brooke's tumour, epithelioma adenoides cysticum, hereditary multiple trichoepithelioma.
Origin: tricho-+ epithelioma
(05 Mar 2000)
brown tumour A mass of fibrous tissue containing haemosiderin-pigmented macrophages and multinucleated giant cells, replacing and expanding part of a bone in primary hyperparathyroidism.
(05 Mar 2000)
Buschke-Lowenstein tumour A large type of condyloma acuminatum found in the anus, vulva, or preputial sac of the penis of middle-aged, uncircumcised men; it tends to extend deeply and recur.
Synonym: Buschke-Lowenstein tumour.
(05 Mar 2000)
calcifying epithelial odontogenic tumour A benign epithelial odontogenic neoplasm derived from the stratum intermedium of the enamel organ; a painless, slowly growing, mixed radiolucent-radiopaque lesion characterised histologically by cords of polyhedral epithelial cells, deposits of amyloid, and spherical calcifications.
Synonym: Pindborg tumour.
(05 Mar 2000)
carcinoid tumour A tumour which secretes excessive amounts of the hormone serotonin. The clinical result is carcinoid syndrome. These tumours may grow anywhere in the gastrointestinal tract (and in the lungs) with approximately 90% in the appendix. The remainder occur in the ileum, stomach, colon or rectum.
(27 Sep 1997)
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