| AST | ASpartate Transaminase(aminoTransferase) = SGOT |
|---|---|
| GOT | Glutamic Oxaloacetic Transaminase |
| SGOT | Serum Glutamic Oxaloacetic Transaminase = AST |
| SGPT | Serum Glutamate(Glutamic) Pyruvate(Pyruvic Acid) Transaminase = ALT |
| EGOT | erythrocytic glutamic oxaloacetic transaminase |
| serum glutamic-pyruvic transaminase | <enzyme> An enzyme that is found primarily in the liver. It is released into the bloodstream as the result of liver damage. Also called the alanine aminotransferase (ALT) or serum glutamic pyruvic transaminase (SGPT). (27 Sep 1997) |
|---|---|
| N6-acetyl-beta-lysine transaminase | <enzyme> Involved in oxidative catabolism of lysine by candida maltosa; forms 2-keto-6-acetamidocaproate Registry number: EC 2.6.1.65 Synonym: n6-acetyllysine transaminase, acl-at, n6-acetyllysine 2-oxoglutarate aminotransferase (26 Jun 1999) |
| D-amino acid transaminase | <enzyme> Catalyses the alpha,beta elimination of the (d)-isomer of beta-chloroalanine or other amino acids to yield pyruvate, chloride and ammonia Registry number: EC 2.6.1.- (26 Jun 1999) |
| ornithine-oxo-acid transaminase | <enzyme> A pyridoxal phosphate enzyme that catalyses the formation of glutamate gamma-saemialdehyde and an l-amino acid from l-ornithine and a 2-keto-acid. Chemical name: L-Ornithine:2-oxo-acid aminotransferase Registry number: EC 2.6.1.13 (12 Dec 1998) |
| ornithine transaminase | <enzyme> An enzyme that will reversibly catalyze the reaction of alpha-ketoglutarate and l-ornithine to form l-glutamate and l-glutamate gamma-saemialdehyde; a deficiency of this enzyme will result in gyrate atrophy of the choroid and retina. Synonym: ornithine transaminase. (05 Mar 2000) |
| transaminase | <enzyme> A subclass of enzymes that catalyse the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally 2 keto acid) in a cyclic process using pyridoxal phosphate as cofactor, for example aspartate amino transferase catalyses the reaction: aspartate + ketoglutarate = oxaloacetate + glutamate. (18 Nov 1997) |
| tyrosine-repressible transaminase | <enzyme> From E coli; catalyses the amination of 2-ketoisocaproate to leucine; encoded by tyrb; a functional leuabcd operon is required for leucine synthesis by this enzyme Registry number: EC 2.6.1.- Synonym: transaminase d, tyrosine-2-ketoisocaproate aminotransferase (26 Jun 1999) |
| tyrosine transaminase | <enzyme> An enzyme that catalyses the conversion of l-tyrosine and 2-oxoglutarate to 4-hydroxyphenylpyruvate and l-glutamate. It is a pyridoxal-phosphate protein. L-phenylalanine can act instead of l-tyrosine. The mitochondrial enzyme may be identical with aspartate transaminase (ec 2.6.1.1.). Chemical name: L-Tyrosine:2-oxoglutarate aminotransferase Registry number: EC 2.6.1.5 (12 Dec 1998) |
| 2,4-diaminobutyric acid transaminase | <enzyme> Catalyses conversion of l-aspartate beta-saemialdehyde to l-2,4-diaminobutyric acid Registry number: EC 2.6.1.46 Synonym: ectb gene product (26 Jun 1999) |
| 4-aminobutyrate transaminase | <enzyme> An enzyme that converts brain gamma-aminobutyric acid (gaba) into succinate saemialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine. Chemical name: 4-Aminobutanoate:2-oxoglutarate aminotransferase Registry number: EC 2.6.1.19 (12 Dec 1998) |
| Addison's clinical planes | A series of plane's used as landmarks in thoracoabdominal topography; the trunk is divided vertically by a median plane from the upper border of the manubrium of the sternum to the pubic symphysis, by a lateral plane drawn vertically on either side through a point half way between the anterior superior iliac spine and the median plane at the interspinal plane, and by an interspinal plane passing vertically through the anterior superior iliac spine on either side; transversely the trunk is divided by a transthoracic plane passing across the thorax 3.2 cm above the lower border of the body of the sternum, by a transpyloric plane midway between the jugular notch of the sternum and the pubic symphysis, corresponding to the disc between the first and second lumbar vertebrae, and by an intertubercular plane passing through the iliac tubercles and cutting usually the fifth lumbar vertebra; the plane's formed on these lines, and also on transverse plane's cutting the upper edge of the manubrium and the upper edge of the pubic symphysis, constitute the clinical plane's of Addison. (05 Mar 2000) |
| pathology, clinical | A subspecialty of pathology which deals with the laboratory analysis of specimens of human blood and other fluids. (12 Dec 1998) |
| chemistry, clinical | The specialty of analytical chemistry applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy. (12 Dec 1998) |
| pharmacology, clinical | The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans. (12 Dec 1998) |
| phase I clinical trial | <pharmacology> The earliest stage clinical trial for studying an experimental drug in humans. Phase I trials are generally comparatively small and are used to determine toxicity and maximum dose. They provide an initial evaluation of a drug's safety and pharmacokinetics-how the drug is absorbed, what tissues it reaches and how long it takes to leave the body. Such studies also usually test various doses of the drug (dose-ranging) to obtain an indication of the appropriate dose to use in later studies. The patients in these trials usually have advanced disease and have already received best available chemotherapy, therefore, seeing a repose is significant partially because this means there is a lack of cross-resistance between two anti-cancer drugs. (31 Dec 1997) |