| 영문 | cell-mediated immunity | 한글 | 세포매개면역 |
|---|---|---|---|
| 설명 | 면역이란 신체를 외부의 물질로부터 보호하는 행위를 말한다. 여기에는 특이적 면역과 비특이적 면역의 두 가지가 있다. 비특이적 면역이라함은 특정한 물질에 관계하는 면역이 아니라 특정 대상이 없이 모든 외부 물체에 작용할 수 있는 면역을 말한다. 여기에는 소변의 흐름, 눈물의 흐름, 피부의 비투과성 등의 기계적인 것도 포함되고 피속에 돌아다니는 세포 중에서 비특이적으로 외부의 물질을 포식하는 세포들(예를 들면 큰포식세포(macrophage)의 활동도 포함이 된다. 세포매개면역이란 특이한 물질을 감지할 수 있는 세포를 생성하게 하여 그것으로 하여금 그 물질을 포식하게 하는 것을 말한다. |
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| 영문 | nerve cell | 한글 | 신경세포 |
|---|---|---|---|
| 설명 | 신경세포는 올바른 신경전달을 위한 각 부분별로 나뉘어져 있다. 신경세포에서는 전해져오는 자극을 전기적인 신호로 바뀌어 보내거나 받게 된다. 이런 전기적인 현상은 각 신경세포내에 존재하는 각 이온채널(ion channel: ion이란 나트륨, 칼륨 등을 지칭하는 말들로써, 이들이 세포막에 의해 나뉘어질 때 생기는 전압차가 전기적 자극을 일으키고 유지하는데 결정적인 역할을 한다)들의 작용에 의해 이루어지게 된다. |
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| 영문 | glia cell | 한글 | 아교세포 |
|---|---|---|---|
| 설명 | 신경세포 사이에서 그물구조를 이루며 이를 지지하는 조직. 신경아교세포는 신경모세포와 갈라진 아교모세포가 다시 여러 형태로 분화-성장한 것이다. 뇌실이나 척수중심관의 벽을 덮고 원주상 또는 입방형이며, 초기에는 유리면에 섬모가 있다. 대형세포는 별뇌실막세포는 아교세포라고 하며, 신경세포나 신경섬유 사이에 산재한다. 그 외에 희소돌기아교세포도 포함된다. |
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| 영문 | reserve cell | 한글 | 예비세포 |
|---|---|---|---|
| 설명 | 일반적으로 상피조직에서 이미 있던 상피세포가 손상을 받아 사멸하면 매꿔지는 그 밑에 있는 미분화세포 예를 들면, 기관지 내표면을 덮는 중층 원주 상피의 기저에 있는 작은 미분화 상피 세포. |
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| 영문 | stem cell | 한글 | 줄기세포, 간세포 |
|---|---|---|---|
| 설명 | 자기 복제를 하여 자신을 존속시키면서 한편으로는 증식과 분화를 하여 새로운 세포를 형성하는 세포로서 조혈줄기세포가 대표적이다. 조혈줄기세포는 골수에 있는 세포로서 모든 혈구세포가 여기에서 분화되어 발생한다. |
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| PEP | peptidase; phospho(enol)pyruvate; peer evaluation program; phosphoenolpyruvate; pigmentation, edema,... |
|---|---|
| ADCC cell | Antibody Dependent Cellular(= Cell-Mediated) Cytotoxicity cell |
| HCG, hCG | Human Chorionic Gonadotropin; 사람융모성성선자극호르몬 1. Placental Glycoprotein Hormone &nbs... |
| Th cell | helper T cell(= T4 cell) |
| Ts cell | suppressor T cell(= T8 cell) |
| CGE | Capillary Gel Electrophoresis |
|---|---|
| CZE | Capillary Zone Electrophoresis |
| CAE | Capillary array electrophoresis |
| CE-LIF | Capillary electrophoresis with laser-induced fluorescence detection |
| CE-ESI-MS | Capillary electrophoresis-electrospray ionization mass spectrometry |
| pulse-field gel electrophoresis | Gel electrophoresis in which, after electrophoretic migration has begun, the current is briefly stopped and reapplied in a different orientation; allows for the purification of long DNA molecules. Synonym: pulsed-field gel electrophoresis. (05 Mar 2000) |
|---|---|
| serum immunoglobulin electrophoresis | A test that detects and measures the various immunoglobulins in the blood. In the normal assay no monoclonal antibodies are detected. In multiple myeloma and chronic lymphocytic leukaemia a single clone of lymphocytes can produce one type of immunoglobulin that is detected in the electrophoresis as monoclonal (made by one cell clone). (27 Sep 1997) |
| disc electrophoresis | Short for discontinuous electrophoresis, it is a type of polyacrylamide gel electrophoresis. This electrophoresis method uses gels of two different concentrations of polyacrylamide (a synthetic polymer), the one of lower concentration stacked on top of the one with higher concentration, in order to better resolve bands of whatever is being separated (DNA, RNA, or protein) that would otherwise be very close together. (09 Oct 1997) |
| immunoglobulin electrophoresis | <immunology, investigation> A test that detects and measures the various immunoglobulins in the blood. In the normal assay no monoclonal antibodies are detected but in multiple myeloma and chronic lymphocytic leukaemia a single clone of lymphocytes can produce one type of immunoglobulin that is detected in the electrophoresis as monoclonal (made by one cell clone). (30 Mar 1998) |
| isoenzyme electrophoresis | Electrophoretic separation of serum enzymes; separation of lactate dehydrogenase and creatine phosphokinase is commonly used for diagnosis of acute myocardial infarction. (05 Mar 2000) |
| thin-layer electrophoresis | Electrophoretic migrations (separations) through a thin layer of inert material, such as cellulose, supported on a glass or plastic plate. (05 Mar 2000) |
| electrophoresis | <technique> Separation of ionic molecules, (principally proteins) by the differential migration through a gel according to the size and ionic charge of the molecules in an electrical field. High resolution techniques normally use a gel support for the fluid phase. Examples of gels used are starch, acrylamide, agarose or mixtures of acrylamide and agarose. Frictional resistance produced by the support causes size, rather than charge alone, to become the major determinant of separation. Smaller molecules with a more negative charge will travel faster and further through the gel toward the anode of an electrophoretic cell when high voltage is applied. Similar molecules will group on the gel. They may be visualised by staining and quantitated, in relative terms, using densitometers which continuously monitor the photometric density of the resulting stain. The electrolyte may be continuous (a single buffer) or discontinuous, where a sample is stacked by means of a buffer discontinuity, before it enters the running gel/ running buffer. The gel may be a single concentration or gradient in which pore size decreases with migration distance. In SDS gel electrophoresis of proteins or electrophoresis of polynucleotides, mobility depends primarily on size and is used to determined molecular weight. In pulse field electrophoresis, two fields are applied alternately at right angles to each other to minimise diffusion mediated spread of large linear polymers. See: electrofocussing, pulse field electrophoresis (01 Dec 1998) |
| electrophoresis, agar gel | Electrophoresis in which agar or agarose gel is used as the diffusion medium. (12 Dec 1998) |
| electrophoresis, capillary | A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of proteins, nucleic acids, and carbohydrates. (12 Dec 1998) |
| electrophoresis, cellulose acetate | Electrophoresis in which cellulose acetate is the diffusion medium. (12 Dec 1998) |
| electrophoresis, disc | Electrophoresis in which discontinuities in both the voltage and pH gradients are introduced by using buffers of different composition and pH in the different parts of the gel column. The term 'disc' was originally used as an abbreviation for 'discontinuous' referring to the buffers employed, and does not have anything to do with the shape of the separated zones. (12 Dec 1998) |
| electrophoresis, gel, pulsed-field | Electrophoresis in which the direction of the electric field is changed periodically. This technique is similar to other electrophoretic methods normally used to separate double-stranded DNA molecules ranging in size up to tens of thousands of base-pairs. However, by alternating the electric field direction one is able to separate DNA molecules up to several million base-pairs in length. (12 Dec 1998) |
| electrophoresis, gel, two-dimensional | Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels. (12 Dec 1998) |
| electrophoresis, paper | Electrophoresis in which paper is used as the diffusion medium. This technique is confined almost entirely to separations of small molecules such as amino acids, peptides, and nucleotides, and relatively high voltages are nearly always used. (12 Dec 1998) |
| electrophoresis, polyacrylamide gel | Electrophoresis in which a polyacrylamide gel is used as the diffusion medium. (12 Dec 1998) |