| 영문 | antianginal drug | 한글 | 항협심증제 |
|---|---|---|---|
| 설명 | 협심증은 심장동맥의 혈류를 좋게하거나 심장이 혈류에 비해서 많은 일을 하는 것을 억제함으로써 치료될 수 있다. ① nitrate계통의 약물: 혈관을 이완시키는 작용을 함으로써 심장동맥의 혈류를 좋게 한다. ② 칼슘통로차단제(verapamil, nifedipine): 모든 근육의 수축에는 Ca이 관여한다. 즉 Ca이 있어야만 근육의 수축이 가능해진다. 그러므로 Ca이 세포속으로 들어가는 것을 억제하는 약제는 근육의 수축을 막는다. 이 약은 심장의 근육에 작용하여 심장 근육의 수축을 억제하며 심장이 과도하게 일하는 것을 막고, 또 심장동맥의 수축에 관여하는 근육에 작용을 하여 심장동맥을 이완시켜서 혈류를 좋게 한다. ③ 베타차단제(beta-blocker): 신체의 운동량이나 기타의 요구에 의해서 심장을 빨리 뛰게하는 신경은 바로 베타-교감신경이다. 교감신경계란 사람이 위급한 상황에서 작용하는 자율신경계이다. 즉 사람이 긴장하거나 싸울 경우에 전형적으로 교감신경계가 작용한다. 즉 심장이 뛰거나 소화가 않되거나 동공이 커지는 것 따위가 바로 교감신경계의 역할이라고 할 수 있다. 이 교감신경계에서 말초장기에 보내는 신경이 교감신경이다. 그러므로 심장에서 심장을 신체에 필요에 따라서 많은 일을 하게하는 신경을 차단할 경우에는 협심증을 치료할 수 있게 된다(심장의 산소나 기타 영양분의 수요를 줄인다). |
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| DA | dark adaptation; dark agouti [rat]; daunomycin; degenerative arthritis; delayed action; Dental Assis... |
|---|---|
| PIXE | particle-induced x-ray emission; proton-induced x-ray emission |
| SIA | serum inhibitory activity; stress-induced analgesia; stress-induced anesthesia; subacute infectious ... |
| DIA | depolarization-induced automaticity; diabetes; diaphorase; diazepam; Drug Information Association |
| DIG | digitalis; digoxin; drug-induced galactorrhea |
| haemangioma-thrombocytopenia syndrome | <syndrome> Thrombocytopenia caused by sequestration and destruction of platelets in a large cavernous haemangioma, usually seen in infants, rare in adults (12 Dec 1998) |
|---|---|
| syndrome, radial aplasia-thrombocytopenia | See syndrome, tar. (12 Dec 1998) |
| syndrome, tetraphocomelia-thrombocytopenia | See syndrome, tar. (12 Dec 1998) |
| syndrome, thrombocytopenia-absent radius | See Syndrome, TAR. (12 Dec 1998) |
| idiopathic thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| immune thrombocytopenia | Thrombocytopenia associated with antiplatelet antibodies. See: isoimmune neonatal thrombocytopenia, autoimmune neonatal thrombocytopenia. (05 Mar 2000) |
| isoimmune neonatal thrombocytopenia | Immune thrombocytopenia resulting from maternal-foetal platelet incompatibility. (05 Mar 2000) |
| tetraphocomelia-thrombocytopenia syndrome | <syndrome> Tar stands for thrombocytopenia (low blood platelets) and aplasia (absence) of the radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the tar child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| thrombocytopenia | <haematology> A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting. Origin: Gr. Penia = poverty (18 Nov 1997) |
| thrombocytopenia-absent radius syndrome | <syndrome> Tar stands for thrombocytopenia (low blood platelets) and aplasia (absence) of the radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the tar child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| thrombocytopenia purpura | <haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages. Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction. Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus. (15 Oct 1997) |
| essential thrombocytopenia | A primary form of thrombocytopenia, in contrast to secondary forms that are associated with metastatic neoplasms, tuberculosis, and leukaemia involving the bone marrow, or with direct suppression of bone marrow by the use of chemical agents, or with other conditions. (05 Mar 2000) |
| abnormalities, radiation-induced | Congenital changes in the morphology of organs produced by exposure to ionizing or non-ionizing radiation. (12 Dec 1998) |
| abortion, induced | Intentional removal of a foetus from the uterus by any of a number of techniques. (popline, 1978) (12 Dec 1998) |
| alpha-chymotrypsin-induced glaucoma | Transient secondary glaucoma following the use of alpha-chymotrypsin in cataract extraction. (05 Mar 2000) |