| thiamine monophosphate | <chemical> Thiamine dihydrogen phosphate ester. The monophosphate ester of thiamine. Synonym: monophosphothiamine; vitamin b1 monophosphate. Chemical name: Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(2-(phosphonooxy)ethyl)-, chloride (12 Dec 1998) |
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| thiamine pyrophosphatase | <enzyme> The coenzyme form of vitamin B1 (thiamine), deficiency of which causes beri beri. Forms the prosthetic group of pyruvate dehydrogenase, _ ketoglutarate dehydrogenase and transketolase, in which it is involved in transfer of a 2 carbon unit. Marker for the trans cisternae of the Golgi complex. (18 Nov 1997) |
| thiamine pyrophosphate | <biochemistry> Co carboxylase. A cofactor that has an unusually acidic carbon atom able to form carbon carbon bonds. Found in pyruvate dehydrogenase and transketolase. (18 Nov 1997) |
| thiamine triphosphate | <chemical> 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, p,p',p''-trioxide. The triphosphate ester of thiamine. In leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation. Chemical name: Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)-, inner salt, P,P',P''-trioxide (12 Dec 1998) |