| estradiol | A hormone (272 D) synthesised mainly in the ovary, but also in the placenta, testis and possibly adrenal cortex. A potent oestrogen. (18 Nov 1997) |
|---|---|
| estradiol 15 alpha-hydroxylase | <enzyme> Catalyses the conversion of estradiol to 15alpha-hydroxyestradiol Registry number: EC 1.14.99.- Synonym: e15a-hydroxylase (26 Jun 1999) |
| estradiol 16 alpha-hydroxylase | <enzyme> Cyp2c11 is a male-specific cyp isoform Registry number: EC 1.14.99.- Synonym: 16 alpha-hydroxylase, estrone 16 alpha-hydroxylase, 16alpha-hydroxylase, steroid 16 alpha-hydroxylase, estrone 3-sulfate 16 alpha-hydroxylase, cytochrome p450cmf, cytochrome p450 2c, cytochrome p450iic11, cytochrome p450(ut-a), cytochrome p4502c-rml5, cytochrome p450h, cytochrome p450(male), cytochrome p4502c, cytochrome p450 2c3, cytochrome p450 2c9, oestrogen 16-hydroxylase, cyp2c3 gene product, cyp2c11 gene product, cytochrome p450 2c11, cyp 2d-9, cytochrome p450(tb), cyp2c9, cytochrome p-450(m1), cyp2c11 (26 Jun 1999) |
| estradiol-17 beta sulfotransferase | <enzyme> Specific for estradiol 17beta; not the same as EC 2.8.2.15 Registry number: EC 2.8.2.- (26 Jun 1999) |
| estradiol antagonists | Compounds which inhibit or antagonise the biosynthesis or action of estradiol. (12 Dec 1998) |
| estradiol benzoate unit | The oestrogenic activity of 0.1 ug of a standard preparation of estradiol benzoate. (05 Mar 2000) |
| estradiol dehydrogenases | <enzyme> Enzymes that catalyze the oxidation of estradiol at the 17-hydroxyl group in the presence of NAD+ or NADP+ to yield estrone and NADH or NADPH. The 17-hydroxyl group can be in the alpha- or beta-configuration.2 Chemical name: Estradiol-17 beta:NAD(P)+ 17-oxidoreductase Registry number: EC 1.1.1.62 (12 Dec 1998) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| ethinyl estradiol | <chemical> (17 alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol. A semisynthetic oestrogen with high oral oestrogenic potency. It is often used as the oestrogenic component in oral contraceptives. Pharmacological action: antineoplastic agent, hormonal, oestrogens, synthetic. Chemical name: 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)- (12 Dec 1998) |
| ethinyl estradiol-norgestrel combination | <chemical> Ethinyl estradiol and norgestrel given in fixed proportions. It has proved to be an effective contraceptive. Pharmacological action: contraceptives, oral, combined, contraceptives, oral, synthetic, contraceptives, postcoital, synthetic. (12 Dec 1998) |
| ethynyl estradiol | 17a-ethynyl-1,3,5-estratriene-3,17-diol;a semisynthetic derivative of 17b-estradiol; active by mouth, with a long half-life, it is among the most potent of known oestrogenic compounds; used in oral contraceptive preparations. Synonym: ethinyl estradiol. Estradiol undecylate, an esterified natural oestrogen for parenteral use. Estradiol valerate, estra-1,3,5(10)-triene-3,17b-diol 17-valerate;same actions and uses as estradiol, but with a prolonged duration of action; administered in sesame oil by intramuscular injection. (05 Mar 2000) |
| abstracting and indexing | Shortening or summarizing of documents; assigning of descriptors for referencing documents. (12 Dec 1998) |
| academies and institutes | Organizations representing specialised fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., national academy of sciences, brookings institution, etc. (12 Dec 1998) |
| accounts payable and receivable | Short-term debt obligations and assets occurring in the regular course of operational transactions. (12 Dec 1998) |
| aged, 80 and over | A person 80 years of age and older. (12 Dec 1998) |