| blocked reading frame | A sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. Synonym: closed reading frame. (05 Mar 2000) |
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| Bradford frame | An oblong rectangular frame made of pipe, over which are stretched transversely two strips of canvas; permits trunk and lower extremities of a bed-ridden patient to move as a unit. (05 Mar 2000) |
| reading frame | One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in nonoverlapping triplets (codons) there are three possible ways of translating a sequence of nucleotides into a protein, each with a different starting point. For example: given the nucleotide sequence: AGCAGCAGC, the three reading frames are: AGC AGC AGC, GCA GCA, CAG CAG. (18 Nov 1997) |
| reading frame, open | An open reading frame in DNA has no termination codon, no signal to stop reading the nucleotide sequence, and so may be translated into protein. (12 Dec 1998) |
| closed reading frame | A sequence of DNA that cannot be translated into a viable protein; usually due to the interruption by one or more termination codons. Synonym: closed reading frame. (05 Mar 2000) |
| picture frame vertebra | Radiographically diminished density of trabecular bone with relative preservation of the cortex, a sign of osteopenia. (05 Mar 2000) |
| Whitman's frame | A frame similar to the Bradford frame, but with curved sides. (05 Mar 2000) |
| space frame | Three-dimensional optical bench that holds laser components stable from vibrational and thermal excursions. (09 Oct 1997) |
| Stryker frame | A frame that holds the patient and permits turning in various planes without individual motion of parts. (05 Mar 2000) |
| occluding frame | <dentistry> A special holder for models of your teeth. The articulator holds the models in the same alignment as your jaw so the orthodontist can look carefully at your bite. (08 Jan 1998) |
| open reading frame | <molecular biology> A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain. (18 Nov 1997) |
| overlapping reading frame | <molecular biology> Start codons in different reading frames which generate different polypeptides from the same DNA sequence. (09 Oct 1997) |
| trial frame | A type of spectacle frame with variable adjustments, for holding trial lenses during refraction. (05 Mar 2000) |
| eulerian frame | <radiobiology> Reference frame which has a fixed coordinate system, as opposed to the Lagrangian Frame, which moves with a fluid. (09 Oct 1997) |
| unidentified reading frame | <molecular biology> A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain. (18 Nov 1997) |