| thalamocortical | Relating to the efferent connections of the thalamus with the cerebral cortex. (05 Mar 2000) |
|---|---|
| thalamocortical fibres | A general term identifying nerve fibres arising from nuclei of the thalamus and projecting to, and terminating in, the cerebral cortex. (05 Mar 2000) |
| thalamolenticular | Relating to the thalamus, usually the dorsal thalamus, and the lenticular nucleus (putamen and globus pallidus). (05 Mar 2000) |
| thalamophora | <zoology> Same as Foraminifera. Origin: NL, fr. Gr. Chamber + to bear. Source: Websters Dictionary (01 Mar 1998) |
| thalamostriate veins | See: inferior thalamostriate veins, superior thalamostriate vein. (05 Mar 2000) |
| thalamotomy | Destruction of a selected portion of the thalamus by stereotaxy for the relief of pain, involuntary movements, epilepsy, and, rarely, emotional disturbances; produces few, if any, neurological deficits or undesirable personality changes. Origin: thalamus + G. Tome, incision (05 Mar 2000) |
| thalamus | <anatomy> Either of two large, ovoid masses, consisting chiefly of grey substance, situated one on each side of and forming part of the lateral wall of the third ventricle. It is divided into two major parts: dorsal and ventral, each of which contains many nuclei. Origin: L., Gr. Thalamos = inner chamber (18 Nov 1997) |
| thalassaemia | <haematology> A genetic form of anaemia in which there is abnormality of the globin portion of haemoglobin. Affected individuals cannot synthesise haemoglobin properly, and they produce small, pale, short-lived red blood cells. Widespread in Mediterranean countries. Origin: Gr. Haima = blood (11 Jan 1998) |
| thalassaemia intermedia | A clinical variant of thalassaemia characterised by an intermediate degree of severity. These patients have severe anaemia but usually do not require regular blood transfusions. Intermedia disorders represented a heterogeneous group of genetic disorders and may include cases with homozygous or heterozygous abnormalities in the beta-globin chain gene. (05 Mar 2000) |
| thalassaemia major | The dire disease also known as beta thalassaemia. The clinical picture of this form of anaemia was first described in 1925 by the paediatrician thomas benton cooley. Other names for the disease are cooley's anaemia and mediterranean anaemia. The term thalassaemia was coined by the nobel prise winning pathologist george whipple and the professor of paediatrics william bradford at u. Of rochester because thalassa in greek means the sea (like the mediterrranean sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of mediterranean origin (for example, from italy and greece). Children with this disease inherit one gene for it from each parent (and so are said to be homozygous for beta thalassaemia). The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth (because at birth we still have predominantly foetal haemoglobin which does not contain beta chains) but the anaemia emerges in the first few months of life and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| thalassaemia minor | Also called thalassaemia trait, thalassaemia minor is the carrier state for beta thalassaemia. People who are carriers (heterozygotes) have just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. (12 Dec 1998) |
| thalassaemia, beta | Also known as thalassaemia major.The clinical picture of this important type of anaemia was first described in 1925 by the paediatrician thomas benton cooley. Other names for the disease are cooley's anaemia and mediterranean anaemia. The name thalassaemia was coined by the nobel prise winning pathologist george whipple and the professor of paediatrics wm bradford at u. Of rochester because thalassa in greek means the sea (like the mediterrranean sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of mediterranean origin (for example, from italy and greece). Children with this disease inherit one gene for it from each parent. The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth because at birth we still have predominantly foetal haemoglobin which does not contain beta chains. The anaemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease. (12 Dec 1998) |
| thalassian | <zoology> Any sea tortoise. Origin: From Gr. The sea. Source: Websters Dictionary (01 Mar 1998) |
| thalassic | <geology> Of or pertaining to the sea; sometimes applied to rocks formed from sediments deposited upon the sea bottom. Origin: Gr. The sea. Source: Websters Dictionary (01 Mar 1998) |
| thalassinian | <zoology> Any species of Thalaassinidae, a family of burrowing macrurous Crustacea, having a long and soft abdomen. Source: Websters Dictionary (01 Mar 1998) |