| 영문 | liver | 한글 | 간 |
|---|---|---|---|
| 설명 | 복강 오른쪽 위에 위치한 암적색의 커다란 장기. 그 반구형으로 융기된 위표면은 오른쪽 가로막 밑면에 밀접하게 부착되어 있으며, 간동맥 및 문맥으로부터 이중의 혈액공급을 받는다. 이 장기는 간의 기능단위인 미세한 소엽(간소엽)으로 되어 있다. 그 다양한 기능에는 혈액의 저장 및 여과, 담즙의 분비, 빌리루빈 및 신체의 다른 곳에서 생성된 물질의 배출, 당의 글리코겐으로의 전환 등을 포함한 다수의 대사기능이 있다. 이 장기는 생명에 필수적이다.  |
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| 영문 | liver cirrhosis | 한글 | 간경화(증) |
|---|---|---|---|
| 설명 | 정상적인 간세포의 많은 부분이 소실이 되고 대신에 섬유조직으로 대치되어 있는 간의 병적 상태를 말한다. 간세포의 많은 손상을 가져오는 모든 병에서 간경화가 일어난다. 그러나 대부분의 간경화의 원인은 간염과 술에 의한 간손상이다. 간경화의 증상은 원인에 따라서 다음과 같은 두 가지로 나눌 수가 있다. 첫째는 우선 간의 기능의 장애에 의한 증상이다. 간세포의 상당수가 섬유조직으로 대체되어 있는 상태이므로 간의 기능의 장애가 생기는 것은 당연하다. 황달 등이 대표적 예라 하겠다. 두번째는 문맥압항진(portal hypertension)에 의한 증상들이다. 위, 작은창자나 큰창자에서 영양분을 흡수하기위한 모세혈관조직은 모두 간으로 연결이 된다. 즉 소화기에서 흡수한 영양분이 가득한 피는 모두 간으로 연결되는데 이것을 문맥계(portal system)라고 한다. 간경화의 경우에는 섬유성조직이 간조직을 거의 대치함으로 정상 간세포내에선 넓은 공간을 차지하던 간내의 혈관들이 섬유조직에 눌리게 된다. 그러면 이것과 연결된 문맥계의 압력도 높아지게 된다. 문맥압의 상승이 있는 경우에는 문맥계에 연결이 되어 있는 모든 부분의 정맥의 압력이 높아지고 정맥의 순환이 정지된 상태가 된다. 지라의 경우도 문맥계에 연결된 장기이므로 문맥압 상승시에는 정맥의 순환이 없어지고, 동맥으로 유입이 되는 혈액은 계속 들어오므로 지라이 커지게 된다. 또 소화기의 모세혈관내에서의 압력도 높아지게 되고 그러면 그 압력에 의해서 많은 양의 수분이 모세혈관밖으로 빠져나오게 된다. 이 수분이 모여 복수가 된다. |
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| 영문 | liver function tests | 한글 | 간기능검사 |
|---|---|---|---|
| 설명 | 혈액검사중 가장 많이 쓰이는 검사법으로 다음 7가지를 검사하게 된다. 혈청콜레스테롤, 총단백질, 알부민, 빌리루빈, GOT/GPT 효소, 알칼리인산분해효소(alkaline phophatase) 등을 검사하게 되는 데 각 검사치에는 모두 의미가 있으며, 이 검사 하나로 간기능의 전반적인 상태에 대해서 알아볼 수 있다. |
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| 영문 | liver biopsy | 한글 | 간생검 |
|---|---|---|---|
| 설명 | 사람이 살아있는 상태에서 병터를 잘라내어 직접 현미경 등으로 보아 진단을 내리는 진단법이다. 간생검은 주로 간염이나 간암의 진단이나, 희귀한 유전병, 선천병 등의 확진에 이용된다. 간염에서는 현재의 간염이 진행성인지 혹은 비진행성인지 또는 이미 간경화상태로 넘어갔는지 등의 여부를 알아보게 된다. |
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| nickel-iron hydrogenase | <enzyme> From desulfovibrio multispirans Registry number: EC 1.12.- Synonym: nife hydrogenase, co-induced hydrogenase, co-tolerant hydrogenase (26 Jun 1999) |
|---|---|
| nickel-iron-selenium hydrogenase | <enzyme> From desulfovibrio baculatus Registry number: EC 1.12.- Synonym: nifese hydrogenase (26 Jun 1999) |
| non-haem iron protein | <biochemistry> Any protein containing iron but not any haem iron; e.g., NADH dehydrogenase. They are often found in oxidation-reduction reactions, and contain iron but no porphyrin groups. (17 Jul 2002) |
| deficiency, iron | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia , whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. (12 Dec 1998) |
| iron | 1. To smooth with an instrument of iron; especially, to smooth, as cloth, with a heated flatiron; sometimes used with out. 2. To shackle with irons; to fetter or handcuff. "Ironed like a malefactor." 3. To furnish or arm with iron; as, to iron a wagon. Origin: Ironed; Ironing. 1. Of, or made of iron; consisting of iron; as, an iron bar, dust. 2. Resembling iron in colour; as, iron blackness. 3. Like iron in hardness, strength, impenetrability, power of endurance, insensibility, etc.; as: Rude; hard; harsh; severe. "Iron years of wars and dangers." (Rowe) "Jove crushed the nations with an iron rod." (Pope) Firm; robust; enduring; as, an iron constitution. Inflexible; unrelenting; as, an iron will. Not to be broken; holding or binding fast; tenacious. "Him death's iron sleep oppressed." Iron is often used in composition, denoting made of iron, relating to iron, of or with iron; producing iron, etc.; resembling iron, literally or figuratively, in some of its properties or characteristics; as, iron-shod, iron-sheathed, iron-fisted, iron-framed, iron-handed, iron-hearted, iron foundry or iron-foundry. Iron age. Common pyrites, or pyrite. See Pyrites. Iron sand, an iron ore in grains, usually the magnetic iron ore, formerly used to sand paper after writing. Iron scale, the thin film which on the surface of wrought iron in the process of forging. It consists essentially of the magnetic oxide of iron, Fe3O4>. Iron works, a furnace where iron is smelted, or a forge, rolling mill, or foundry, where it is made into heavy work, such as shafting, rails, cannon, merchant bar, etc. Origin: AS. Iren, isen. See Iron. 1. <chemistry> The most common and most useful metallic element, being of almost universal occurrence, usually in the form of an oxide (as hematite, magnetite, etc), or a hydrous oxide (as limonite, turgite, etc). It is reduced on an enormous scale in three principal forms; viz, cast iron, steel, and wrought iron. Iron usually appears dark brown, from oxidation or impurity, but when pure, or an fresh surface, is a gray or white metal. It is easily oxidized (rusted) by moisture, and is attacked by many corrosive agents. Symbol Fe (Latin Ferrum). Atomic weight 55.9. Specific gravity, pure iron.86; cast iron.1. In magnetic properties, it is superior to all other substances. The value of iron is largely due to the facility with which it can be worked. Thus, when heated it is malleable and ductile, and can be easily welded and forged at a high temperature. As cast iron, it is easily fusible; as steel, is very tough, and (when tempered) very hard and elastic. Chemically, iron is grouped with cobalt and nickel. Steel is a variety of iron containing more carbon than wrought iron, but less that cast iron. It is made either from wrought iron, by roasting in a packing of carbon (cementation) or from cast iron, by burning off the impurities in a Bessemer converter (then called Bessemer steel), or directly from the iron ore (as in the Siemens rotatory and generating furnace). 2. An instrument or utensil made of iron; chiefly in composition; as, a flatiron, a smoothing iron, etc. "My young soldier, put up your iron." (Shak) 3. Fetters; chains; handcuffs; manacles. "Four of the sufferers were left to rot in irons." (Macaulay) 4. Strength; power; firmness; inflexibility; as, to rule with a rod of iron. Bar iron. See Wrought iron (below). Bog iron, bog ore; limonite. See Bog ore, under Bog. <chemistry> Cast iron, the purest form of iron commonly known in the arts, containing only about half of one per cent of carbon. It is made either directly from the ore, as in the Catalan forge or bloomery, or by purifying (puddling) cast iron in a reverberatory furnace or refinery. It is tough, malleable, and ductile. When formed into bars, it is called bar iron. Origin: OE. Iren, AS. Iren, isen, isern; akin to D. Ijzer, OS. Isarn, OHG. Isarn, isan, G. Eisen, Icel. Isarn, jarn, Sw. & Dan. Jern, and perh. To E. Ice; cf. Ir. Iarann, W. Haiarn, Armor. Houarn. Source: Websters Dictionary (01 Mar 1998) |
| iron-52 | A radioactive iron isotope; a cyclotron-produced positron emitter with a half-life of 8.28 hr, used to study iron metabolism. (05 Mar 2000) |
| iron-55 | An iron isotope; a positron emitter with a half-life of 2.73 years; used (less often than 59Fe) as a tracer in study of iron metabolism and in blood perfusion studies. (05 Mar 2000) |
| iron-59 | An iron isotope; a gamma and beta emitter with a half-life of 44.51 days; used as tracer in study of iron metabolism, determination of blood volume, and in blood transfusion studies. (05 Mar 2000) |
| iron alum | An astringent and styptic. Synonym: ammonium ferric sulfate, ferric alum, iron alum. (05 Mar 2000) |
| iron-binding capacity | The capacity of iron-binding protein in serum (transferrin) to bind serum iron. (05 Mar 2000) |
| iron chelating agents | Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of haemoglobin is an example of a metal chelate found in biological systems. (12 Dec 1998) |
| iron compounds | Inorganic compounds that contain iron as an integral part of the molecule. (12 Dec 1998) |
| iron deficiency | Deficiency of iron results in anaemia because iron is necessary to make haemoglobin, the key molecule in red blood cells responsible for the transport of oxygen. In iron deficiency anaemia, the red cells are unusally small (microcytic) and pale (hypochromic). Characteristic features of iron deficiency anaemia in children include failure to thrive (grow) and increased infections. The treatment of iron deficiency anaemia , whether it be in children or adults, is with iron and iron-containing foods. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the recommended dietary allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. (12 Dec 1998) |
| iron deficiency anaemia | Hypochromic microcytic anaemia characterised by low serum iron, increased serum iron-binding capacity, decreased serum ferritin, and decreased marrow iron stores. Synonym: hypoferric anaemia. (05 Mar 2000) |
| iron dextrin | A complex of dextrin with ferric hydroxide; used intravenously in the treatment of iron deficiency. (05 Mar 2000) |