| U-RNA | uridylic acid ribonucleic acid |
|---|---|
| SAS | sarcoma amplified sequence; self-rating anxiety scale; short arm splint; Sklar Aphasia Scale; sleep ... |
| SCC | self-care center; sequential combination chemotherapy; services for crippled children; short-course ... |
| GIP | 1) Giant cell Interstitial Pneumonia 2) Gastric Inhibitory (Poly)Peptide |
| IPSP | Inhibitory Post-Synaptic Potential; 억제성 시냅스후 전위 |
| inhibitory postsynaptic potential | The change in potential produced in the membrane of the next neuron when an impulse which has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization; the frequency of discharge of a given neuron is determined by the extent to which impulses that lead to excitatory postsynaptic potential's predominate over those that cause inhibitory postsynaptic potential's. (05 Mar 2000) |
|---|---|
| inhibitory synapse | A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell. The most common inhibitory neurotransmitter is GABA, this opens channels in the postsynaptic cell which tend to stabilise its resting potential, thus rendering it less likely to fire. See: excitatory synapse, presynaptic inhibition, postsynaptic inhibition. (18 Nov 1997) |
| Leukaemia inhibitory factor | <growth factor> Polypeptide growth factor or cytokine with wide range of activities. Regulates growth and differentiation of primordial germ cells and embryonic stem cells but has effects on peripheral neurons, osteoblasts, adipocytes and various cells of the myeloid lineage. Given to adult animals induces weight loss, behavioural disorders and bone abnormalities. Many of the effects of LIF in vitro can be mimicked by IL-6, oncostatin M and ciliary neurotrophic factor, all of which interact indirectly with gp130, a shared tranducer subunit. (18 Nov 1997) |
| leukocyte migration-inhibitory factors | Protein factor(s) released by sensitised lymphocytes (and possibly other cells) that inhibit the movement of leukocytes, especially polymorphonuclear cells, away from their site of release. Assays for these factors are used as tests for cellular immunity. Two of the common assays are the leukocyte migration capillary tube technique (lmct) and the leukocyte migration agarose technique (lmat). (12 Dec 1998) |
| bilaterally small, smooth kidneys | <radiology> Generalised atherosclerosis, nephrosclerosis - benign and malignant, atheroembolic renal disease, chronic glomerulonephritis, papillary necrosis, hereditary diseases, hereditary chronic nephritis (Alport's syndrome), medullary cystic disease, amyloidosis (late), arterial hypotension Cf: other urographic patterns (12 Dec 1998) |
| carcinoma, non-small-cell lung | A heterogeneous aggregate of at least three distinct histological types of lung cancer, including squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. They are dealt with collectively because of the shared properties of poor response to conventional chemotherapy and the potential for cure with surgical resection in a fraction of patients. (12 Dec 1998) |
| carcinoma, small cell | An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterised by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. There are admixtures of small cell lung carcinoma with other types of lung cancer. Small cell carcinomas are distinguished by their distinctive biological features, response to chemotherapy and radiotherapy, and by their nearly universal tendency to develop overt or subclinical metastases, which frequently eliminates surgery in most patients. (12 Dec 1998) |
| generalised small bowel disease | <radiology> Hypoproteinaemia, sprue, Whipple (12 Dec 1998) |
| mesenteric portion of small intestine | The freely movable portion of the small intestine supplied with a mesentery, comprising the jejunum and ileum. Synonym: mesenteric portion of small intestine. (05 Mar 2000) |
| ribonucleoproteins, small nuclear | Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm. The u3 snrnp is localised in the nucleolus, where it aligns into base pairs with the 28s rrna precursor in a still unidentified region and functions in pre-rrna processing. The u7 snrnp aligns into base pairs with a conserved sequence in the 3'-end of histone pre-mRNA and is an essential cofactor for the cleavage that creates the mature nonadenylated 3'-end. (12 Dec 1998) |
| ribonucleoproteins, small, u1 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u1 snrnp along with other small ribonucleoproteins (u2, u4-u6, and u5) assemble into spliceosomes that remove introns from pre-mRNA by splicing. The u1 snrnp base pairs with conserved sequence motifs at the 5'-splice site and recognises both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction. (12 Dec 1998) |
| ribonucleoproteins, small, u2 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u2 snrnp along with other small ribonucleoproteins (u1, u4-u6, and u5) assemble into spliceosomes that remove introns from pre-mRNA by splicing. The u2 snrnp base pairs with conserved sequence motifs at the branch point, which associates with a heat- and rnaase-sensitive factor in an early step of splicing. (12 Dec 1998) |
| ribonucleoproteins, small, u4-u6 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u4-u6 snrnp along with the u5 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to form mature spliceosomes. There is also evidence for the existence of individual u4 or u6 snrnps in addition to their organization as a u4-u6 snrnp. (12 Dec 1998) |
| ribonucleoproteins, small, u5 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u5 snrnp along with u4-u6 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to form mature spliceosomes. (12 Dec 1998) |
| mucosa of small intestine | The mucous coat of the small intestine. Synonym: tunica mucosa intestini tenuis. (05 Mar 2000) |