| slow virus | 1. <virology> Specifically one of the Lentivirinae 2. Any virus causing a disease that has a very slow onset. Diseases such as sub acute spongiform encephalopathy, Aleutian disease of mink, scrapie, kuru and Creutzfeldt Jacob disease may be caused by slow viruses. See: prion. (18 Nov 1997) |
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| slow virus disease | A disease that follows a slow, progressive course spanning months to years, frequently involving the central nervous system, and ultimately leading to death, such as visna and maedi of sheep, caused by viruses of the subfamily Lentivirinae (family Retroviridae), and subacute sclerosing panencephalitis, seemingly caused by the measles virus; spongiform encephalopathies including kuru of man, scrapie of sheep, and transmissible encephalopathy of mink may also be classified under slow virus disease but their respective aetiologic agents have not been adequately characterised. (05 Mar 2000) |
| slow virus diseases | Diseases of viral origin, characterised by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as subacute sclerosing panencephalitis, progressive multifocal leukoencephalopathy (leukoencephalopathy, progressive multifocal), and aids. Diseases produced by unconventional agents were originally considered part of this group. They are now called prion diseases. (12 Dec 1998) |