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intrinsic pathway <haematology> Initiation of blood clotting as a result of factors released from damaged tissue, as opposed to contact with a foreign surface (the intrinsic pathway).
Tissue thromboplastin (Factor III) in conjunction with Factor VII proconvertin) will activate Factor X that, once activated, converts prothrombin to thrombin.
(27 Jun 1999)
intrinsic proteins Proteins that cannot be easily separated from a biomembrane.
Synonym: intrinsic proteins.
(05 Mar 2000)
intrinsic reflex A reflex muscular contraction elicited by the application of a stimulus, usually stretching, to the muscle itself as opposed to a muscular contraction caused by an extrinsic stimulus, e.g., skin, as in the abdominal skin reflex's.
(05 Mar 2000)
intrinsic sphincter A thickening of the circular fibres of the muscular coat of an organ.
(05 Mar 2000)
intrinsic sympathomimetic activity The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system.
(05 Mar 2000)
tonoplast intrinsic protein <protein> Plant protein, closely related to major intrinsic protein. Found in plant storage vacuolar membranes.
(18 Nov 1997)
rapid eye movement sleep REM sleep, that state of deep sleep in which rapid eye movements, alert EEG pattern, and dreaming occur; several central and autonomic functions are distinctive during this state.
(05 Mar 2000)
paradoxical sleep A deep sleep, with a brain wave pattern more like that of waking states than of other states of sleep, which occurs during rapid eye movement sleep.
(05 Mar 2000)
paroxysmal sleep <neurology> A disorder of sleep associated with excessive daytime sleepiness, involuntary daytime sleep episodes, disturbed nocturnal sleep and cataplexy.
Narcolepsy affects over 100,000 people in the United States and appears to have a genetic basis.
Symptoms usually begin in the patients twenties. Treatment often includes the use of amphetamines and-or tricyclic antidepressants.
(27 Sep 1997)
REM stage sleep <physiology> A stage of deep sleep that is accompanied by rapid eye movement and muscle paralysis. Vivid dreams can be recalled in over 80% of patients who awake from REM stage sleep.
(27 Sep 1997)
central sleep apnoea <neurology> A form of sleep apnoea which from the lack of neurologic stimulation to breathe.
(12 Jan 1998)
mixed sleep apnoea <chest medicine> A form of sleep apnoea where there is exists a combination of obstructive and central sleep apnoea syndromes.
(13 Nov 1997)
winter sleep The dormant state in which some animal species pass the winter. It is characterised by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs. It is a natural physiological process in many warm-blooded animals.
(12 Dec 1998)
multiple sleep latency test A test of the propensity to fall asleep, done by performing polysomnography during multiple brief opportunities to sleep.
(05 Mar 2000)
crescendo sleep Normal sleep, marked by a gradual increase in movements of the sleeper during the course of the night.
(05 Mar 2000)
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