| adult T-cell lymphoma | <tumour> An acute or subacute disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcaemia. Synonym: adult T-cell leukaemia. (05 Mar 2000) |
|---|---|
| adult tuberculosis | Tuberculosis found in adults and characterised by lesions near the apex of an upper lobe, which may cavitate or heal with scarring without spreading to lymph nodes; theoretically, secondary tuberculosis may be due to exogenous reinfection or to reactivation of a dormant endogenous infection. Synonym: adult tuberculosis, postprimary tuberculosis, reinfection tuberculosis. (05 Mar 2000) |
| respiratory distress syndrome, adult | A syndrome of life-threatening progressive pulmonary insufficiency in the absence of known pulmonary disease, usually following a systemic insult such as surgery or major trauma. (12 Dec 1998) |
| coeliac disease, adult | See Coeliac sprue. (12 Dec 1998) |
| still's disease, adult-onset | Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalised lymphadenopathy and hepatosplenomegaly are more prominent. (12 Dec 1998) |
| disease, adult coeliac | This condition results from an immune (allergic) reaction to gluten, a protein found in wheat and related grains and present in many foods that we eat. Sprue causes impaired absorption and digestion of nutrients through the small intestine. Symptoms include requent diarrhoea and weight loss. A skin condition called dermatitis herpetiformis can be associated with coeliac sprue. The most accurate diagnostic test for sprue is a biopsy of the involved small bowel. Treatment is to avoid gluten in the diet. Medications are used for refractory (stubborn) sprue. Known under a number of other names, including coeliac sprue. (12 Dec 1998) |
| anaplastic large cell lymphoma | <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2). Synonym: Ki-1+ lymphoma. (05 Mar 2000) |
| bilateral large kidneys | <radiology> Autosomal dominant (adult) polycystic disease, lymphoma Cf: other urographic patterns (12 Dec 1998) |
| carcinoma, large cell | A tumour of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (12 Dec 1998) |
| papillary adenoma of large intestine | <tumour> Appears as a solitary sessile, often large, tumour of colonic mucosa composed of mucinous epithelium covering delicate vascular projections; malignant change occurs frequently; hypersecretion occurs rarely. Also known as adenoma. Synonym: papillary adenoma of large intestine. (05 Mar 2000) |
| ribulose-1,5-bisphosphate carboxylase-oxygenase large subunit epsilonN-methyltransferase | <enzyme> An aspect of EC 2.1.1.43; trimethylates lys-14 of rubisco Registry number: EC 2.1.1.- Synonym: rubisco lsmt, rubisco large subunit lysine n-methyltransferase (26 Jun 1999) |
| the large mass of the telencephalon | On either side of the midline, consisting of the cerebral cortex and its associated fibre systems, together with the deeper-lying subcortical telencephalic nuclei (i.e., basal ganglia [nuclei]). (05 Mar 2000) |
| unilateral large kidney | <radiology> Multifocal: xanthogranulomatous pyelonephritis (XGP), malakoplakia, multicystic dysplastic kidney Cf: other urographic patterns smooth kidney: renal vein thrombosis, acute arterial infarction, obstructive uropathy, acute bacterial nephritis, compensatory hypertrophy, duplicated pelvocalyceal system Cf: other urographic patterns multifocal: solid neoplastic mass, malignant, adenocarcinoma, adult nephroblastoma, invasive transitional cell carcinoma, sarcoma, metastasis, benign, hamartoma, adenoma, mesenchymal tumour cystic mass, simple cyst, focal hydronephrosis, multilocular cystic nephroma, arteriovenous malformation Cf: other urographic patterns (12 Dec 1998) |
| follicular predominantly large cell lymphoma | <tumour> A B-cell lymphoma of intermediate malignancy. (05 Mar 2000) |
| large | 1. Exceeding most other things of like in bulk, capacity, quantity, superficial dimensions, or number of constituent units; big; great; capacious; extensive; opposed to small; as, a nlarge horse; a large house or room; a large lake or pool; a large jug or spoon; a large vineyard; a large army; a large city. For linear dimensions, and mere extent, great, and not large, is used as a qualifying word; as, great length, breadth, depth; a great distance; a great height. 2. Abundant; ample; as, a large supply of provisions. "We hare yet large day." (Milton) 3. Full in statement; diffuse; full; profuse. "I might be very large upon the importance and advantages of education." (Felton) 4. Having more than usual power or capacity; having broad sympathies and generous impulses; comprehensive; said of the mind and heart. 5. Free; unembarrassed. "Of burdens all he set the Paynims large." (Fairfax) 6. Unrestrained by decorum; said of language. "Some large jests he will make." 7. Prodigal in expending; lavish. 8. Crossing the line of a ship's course in a favorable direction; said of the wind when it is abeam, or between the beam and the quarter. at large. Without restraint or confinement; as, to go at large; to be left at large. Diffusely; fully; in the full extent; as, to discourse on a subject at large. Common at large. See Common, Electors at large, Representative at large, electors, or a representative, as in Congress, chosen to represent the whole of a State, in distinction from those chosen to represent particular districts in a State. To give, go, run, or sail large, to have the wind crossing the direction of a vessel's course in such a way that the sails feel its full force, and the vessel gains its highest speed. See Large. Synonym: Big, bulky, huge, capacious, comprehensive, ample, abundant, plentiful, populous, copious, diffusive, liberal. Origin: F, fr. L. Largus. Cf. Largo. Source: Websters Dictionary (01 Mar 1998) |