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myo-inositol-1-phosphate synthase <enzyme> An enzyme that catalyses the formation of myo-inositol-1-phosphate from glucose-6-phosphate in the presence of NAD.
Chemical name: 1L-myo-Inositol-1-phosphate lyase (isomerizing)
Registry number: EC 5.5.1.4
(12 Dec 1998)
myo-inositol-trisphosphate 3-kinase <enzyme> Converts inositol triphosphate to 1,3,4,5-tetrakisphosphate
Registry number: EC 2.7.1.127
Synonym: inositol 1,4,5-triphosphate kinase, 1,4,5-intp kinase, inositol(1,4,5)p3 3-kinase, myo-inositol 1,4,5-triphosphate-3-kinase, inositol 1,4,5-trisphosphate kinase
(26 Jun 1999)
myo-inositol-trisphosphate 6-kinase <enzyme> Forms inositol 1,3,4,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate in a ratio of 5:1
Registry number: EC 2.7.1.133
Synonym: inositol 1,3,4-p3 kinase, ins 1,3,4-p3 kinase, myo-inositol 1,3,4-tris phosphate 6-kinase, inositol-1,3,4-trisphosphate 5,6-kinase, inositol-trisphosphate 6-kinase
(26 Jun 1999)
cyclic inositol phosphate 1, 2 cyclic derivatives of inositol phosphatide that are invariably formed during enzymic hydrolysis of phosphatidyl inositol species. Have been proposed as second messengers in hormone activated pathways.
(18 Nov 1997)
D-myo-inositol-3-phosphate synthase <enzyme> Catalyses conversion of d-glucose-6-phosphate to d-myo-inositol-3-phosphate
Registry number: EC 5.5.1.-
Synonym: inositol-3-phosphate synthase, ins3p synthase
(26 Jun 1999)
inositol A cyclic hexahydric alcohol with 6 possible isomers. The biologically active form is myo inositol.
(18 Nov 1997)
inositol 1,2,3,4,6-pentakisphosphate-2-phoshomonoesterase <enzyme> Metabolises ins(1,2,3,4,6)p5 to ins(1,3,4,6)p4
Registry number: EC 3.1.3.-
Synonym: 1,2,3,4,5-insp5-2-p monoesterase
(26 Jun 1999)
inositol 1,3,4,5-tetrakisphosphate phosphomonoesterase <enzyme> Rat liver enzyme forms inositol 1,3,4-triphosphate
Registry number: EC 3.1.3.-
Synonym: inositol tetrakisphosphate phosphomonoesterase, ins(1,3,4,5)p4 phosphomonoesterase, ins(1,3,4,5)p4 5-phosphatase, 1,4,5-triphosphate-1,2,4,5-tetrakisphosphate 5-phosphatase, inositol 1,3,4,5-polyphosphate 5-phosphatase
(26 Jun 1999)
inositol 1,3,4-trisphosphate 5-6 kinase <enzyme> Consider also EC 2.7.1.133 or EC 2.7.1.139
Registry number: EC 2.7.1.-
Synonym: ins(1,3,4)p3 5-6 kinase
(26 Jun 1999)
inositol 1,4,5-trisphosphate <chemical> Intracellular messenger formed by the action of phospholipase c on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of b kinase or calmodulin.
Chemical name: D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)
(12 Dec 1998)
inositol-1,4-bisphosphate 4-phosphohydrolase <enzyme> Soluble rat brain enzyme highly specific for inositol 1,4-bisphosphate; does not act on inositol 1-phosphate or inositol 1,4,5-trisphosphate
Registry number: EC 3.1.3.-
Synonym: ibp 4-phosphohydrolase
(26 Jun 1999)
inositol 1-alpha-galactosyltransferase <enzyme> Catalyses conversion of udpgalactose plus myo-inositol to galactinol plus udp
Registry number: EC 2.4.1.123
Synonym: galactinol synthase
(26 Jun 1999)
inositol 3 kinase <enzyme> See phosphatidyl inositol 3 kinase.
(18 Nov 1997)
inositol cyclic 1,2-phosphate 1-phosphodiesterase <enzyme> Converts inositol 1:2-cyclic phosphate to inositol 2-phosphate; do not confuse with inositol 1,2 cyclic-phosphate 2-phosphohydrolase see annexin III
Registry number: EC 3.1.4.-
Synonym: cins(1,2)p hydrolase II
(26 Jun 1999)
inositol hexakisphosphate kinase <enzyme> 54-kD enzyme that catalyses formation of diphosphoinositol pentakisphosphate (pp-ip5) from inositol hexakisphosphate; the reverse reaction acts as an ATP synthase
Registry number: EC 2.7.4.-
Synonym: ip(6) kinase
(26 Jun 1999)
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