| RNA, ribosomal, 16s | Constituent of 30s subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16s rrna is involved in initiation of polypeptide synthesis. (12 Dec 1998) |
|---|---|
| RNA, ribosomal, 18s | Constituent of the 40s subunit of eukaryotic ribosomes. 18s rrna is involved in the initiation of polypeptide synthesis in eukaryotes. (12 Dec 1998) |
| RNA, ribosomal, 23s | Constituent of 50s subunit of prokaryotic ribosomes containing about 3200 nucleotides. 23s rrna is involved in the initiation of polypeptide synthesis. (12 Dec 1998) |
| RNA, ribosomal, 28s | Constituent of the 60s subunit of eukaryotic ribosomes. 28s rrna is involved in the initiation of polypeptide synthesis in eukaryotes. (12 Dec 1998) |
| RNA, ribosomal, 5.8s | Constituent of the 60s subunit of eukaryotic ribosomes. 5.8s rrna is involved in the initiation of polypeptide synthesis in eukaryotes. (12 Dec 1998) |
| RNA, ribosomal, 5s | Constituent of the 50s subunit of prokaryotic ribosomes containing about 120 nucleotides and 34 proteins. It is also a constituent of the 60s subunit of eukaryotic ribosomes. 5s rrna is involved in initiation of polypeptide synthesis. (12 Dec 1998) |
| pre-ribosomal RNA endoribonuclease | <enzyme> Substrate is pre-rrna Registry number: EC 3.1.26.- Synonym: pre-rrna endoribonuclease (26 Jun 1999) |
| sisomicin-gentamicin resistance ribosomal RNA methylase | <enzyme> Catalyses the methylation of 30s ribosomal units to confer sisomicin-gentamicin resistance in micromonospora zionensis Registry number: EC 2.1.1.- Synonym: sgm gene product, sgm methylase (26 Jun 1999) |
| non-ribosomal peptide synthase | <enzyme> Nrp - non-ribosomal peptide/polyketide; locus nrp is mutated in a swarming-defective proteus mirabilis strain; 249 amino acid residues, mw 29.7 kD; amimo acid sequence given in first source Registry number: EC 6.3.2.- Synonym: nrpg protein, nrpg gene product (26 Jun 1999) |
| DNA, ribosomal | DNA sequences encoding ribosomal RNA. These sequences regulate amplification and transcription initiation and contain transcribed and nontranscribed spacer segments. (12 Dec 1998) |
| frameshifting, ribosomal | A directed change in translational reading frame that allows the production of a single protein from two or more overlapping genes. The process is programmed by the nucleotide sequence of the mRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in viruses (especially retroviruses), retrotransposons, and bacterial insertion elements but also in some cellular genes. (12 Dec 1998) |
| acetoacetyl-acyl carrier protein synthase | <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin Registry number: EC 2.3.1.- Synonym: acetoacetyl-acp synthase (26 Jun 1999) |
| acid soluble spore protein | <molecular biology> A DNA binding protein in the spores of some bacteria, thought to stabilise the DNA in an A configuration, so protecting it from cleavage by enzymes or UV light. (18 Nov 1997) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acyl-(acyl-carrier-protein)-phospholipid acyltransferase | <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine Registry number: EC 2.3.1.40 Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase (26 Jun 1999) |