| CTTAC | clinical trials and treatment advisory committee |
|---|---|
| EHPAC | Emergency Health Preparedness Advisory Committee |
| FACOSH | Federal Advisory Committee on Occupational Safety and Health |
| GMENAC | Graduate Medical Education National Advisory Committee |
| IHAC | Industrial Health and Advisory Committee |
| recombinant fusion proteins | Proteins that are the result of genetic engineering. A regulatory part or promoter of one or more genes is combined with a structural gene. The fusion protein is formed after transcription and translation of the fused gene. This type of fusion protein is used in the study of gene regulation or structure-activity relationships. They might also be used clinically as targeted toxins (immunotoxins). (12 Dec 1998) |
|---|---|
| recombinant proteins | Proteins prepared by recombinant DNA technology. (12 Dec 1998) |
| recombinant strain | <molecular biology> A cell or an individual with a new combination of genes not found together in either parent, usually applied to linked genes. (18 Nov 1997) |
| recombinant vector | A vector into which a foreign DNA has been inserted. Synonym: vector. (05 Mar 2000) |
| clones, recombinant | Clones containing recombinant DNA molecules. (12 Dec 1998) |
| somatotropins, recombinant | Somatotropin prepared by recombinant DNA technology. Several different forms have been developed from humans, cows, and pigs. They have been used to help stimulate growth. (12 Dec 1998) |
| erythropoietin, recombinant | Erythropoietin prepared by recombinant DNA technology. (12 Dec 1998) |
| A-DNA | A form of DNA in which the helix is right-handed and the overall appearance is short and broad. (05 Mar 2000) |
| a-form DNA | <molecular biology> One of several forms that can be assumed by a double helix. A-DNA is stable in dehydrated conditions. This form is less common than the dominant form found under physiological conditions -- beta-DNA. This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA. (09 Oct 1997) |
| antisense DNA | <molecular biology> A synthetic DNA strand that is complementary to a particular strand of target DNA with a complementary sequence of bases. This results in preventing expression of the gene encoded. These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. (14 Nov 1997) |
| apurinic DNA | <molecular biology> A DNA molecule that has lost adenine and guanine, its purine bases. Apurinic DNA can be produced by treating the DNA with acid. (09 Oct 1997) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| bacteriophage T7 induced DNA polymerase | <enzyme> Complex of two proteins, phage gene 5 protein and E coli thioredoxin Registry number: EC 2.7.7.- Synonym: t7 phage DNA polymerase, sequenase, t7 DNA polymerase, thermo sequenase (26 Jun 1999) |
| base in DNA | A unit of the DNA. There are 4 bases: adenine (A), guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is the genetic code. (12 Dec 1998) |
| beta-DNA | <molecular biology> The normal form of DNA found in organisms, which exists as a right-handed helix. (09 Oct 1997) |