| PLDR | potentially lethal damage repair |
|---|---|
| PVR | peripheral vascular resistance; perspective volume rendering; poliovirus receptor; postvoiding resid... |
| RAG | ragweed; recombination activating gene |
| REC | receptor; recombination, recombinant [chromosome] |
| RPLD | repair of potentially lethal damage |
| somatic recombination | One of the mechanisms used to generate diversity in antibody production is to rearrange the DNA in B-cells during their differentiation, a process that involves cutting and splicing the immunoglobulin genes. Somatic recombination via homologous crossing over occurs at a low frequency in Aspergillus, Drosphilia and Saccharomyces and in mammalian cells in culture. It may be detected through the production of homozygous patches or sectors after mitosis of cells heterozygous for suitable marker genes. (18 Nov 1997) |
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| dissociative recombination | <radiobiology> The combination of an electron with a positive molecular ion, followed by dissociation of the molecule in which the resulting atoms/molecules carry off the excess energy released in the recombination. (09 Oct 1997) |
| DNA-directed DNA polymerase | <enzyme> DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. Chemical name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) Registry number: EC 2.7.7.7 (12 Dec 1998) |
| arthroscopic knee repair | <orthopaedics> A fibreoptic procedure, known as arthroscopy, is used in the surgical repair of any of several knee ligaments including the anterior cruciate ligament (ACL), lateral or medial meniscus, lateral collateral or medial collateral ligament. Recovery from this procedure is based largely on the ligament repaired and can be highly variable. (27 Sep 1997) |
| recombinatorial repair | The incorporation of corresponding DNA of a DNA segment from an identical DNA molecule for the purpose of replacing a damaged segment of DNA. (05 Mar 2000) |
| repair | 1. To restore to a sound or good state after decay, injury, dilapidation, or partial destruction; to renew; to restore; to mend; as, to repair a house, a road, a shoe, or a ship; to repair a shattered fortune. "Secret refreshings that repair his strength." (Milton) "Do thou, as thou art wont, repair My heart with gladness." (Wordsworth) 2. To make amends for, as for an injury, by an equivalent; to indemnify for; as, to repair a loss or damage. "I 'll repair the misery thou dost bear." (Shak) Synonym: restore, recover, renew, amend, mend, retrieve, recruit. Origin: F. Reparer, L. Reparare; pref. Re- re- + parare to prepare. See Pare, and cf. Reparation. Source: Websters Dictionary (01 Mar 1998) |
| repair enzyme | <enzyme, molecular biology> An enzyme that can catalyze the repair of damaged DNA; e.g., DNA ligase. (05 Mar 2000) |
| repair nuclease | <enzyme, molecular biology> Class of enzymes involved in DNA repair. It includes endonucleases that recognise a site of damage or an incorrect base pairing and cut it out and exonucleases that remove neighbouring nucleotides on one strand. These are then replaced by a DNA polymerase. (18 Nov 1997) |
| chemical repair | Conversion of a free radical to a stable molecule. (05 Mar 2000) |
| mismatch repair | <molecular biology> A DNA repair system that detects and replaces wrongly paired, mismatched, bases in newly replicated DNA. E. Coli has a mismatch correction enzyme coded for by three genes mutH, mutL and mutS, that is directed to the newly synthesised strand and removes a segment of that strand including the incorrect nucleotide. The gap is then filled by DNA polymerase. (18 Nov 1997) |
| hernia repair | <surgery> The surgical repair of a hernia. This surgery can be done under local or general anaesthesia. May be performed using a conventional incision or using a fibreoptic laparoscope. (27 Sep 1997) |
| SOS repair | A system that repairs severely damaged bases in DNA by base excision and replacement, even if there is no template to guide base selection. This process is a last resort for repair, and is often the cause of mutations. Synonym: error-prone repair. (05 Mar 2000) |
| dental prosthesis repair | The process of reuniting or replacing a broken or worn dental prosthesis or its part. (12 Dec 1998) |
| denture repair | The process of reuniting or replacing broken or worn parts of a denture. (12 Dec 1998) |
| error-prone repair | <molecular biology> A type of DNA repair which occurs when both nucleotides in a base pair are missing, such that it is not possible to maintain accuracy. In general, the repair proteins replace the missing nucleotides randomly. The idea is that bad DNA is better than no DNA at all. (06 Mar 1998) |