| HARS | histidyl-RNA synthetase |
|---|---|
| poly-IC, | poly-I:C copolymer of polyinosinic and polycytidylic acids; synthetic RNA polymer |
| RNA | radionuclide angiography; Registered Nurse Anesthetist; ribonucleic acid; rough, noncapsulated, avir... |
| U-RNA | uridylic acid ribonucleic acid |
| NB | New-Born |
| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
|---|---|
| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| acceptor RNA | rNA |
| antisense RNA | <molecular biology> A complementary RNA sequence that binds to (and thus blocks the transcription of) a naturally-occuring (sense) messenger RNA molecule. These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. (09 Oct 1997) |
| bacteriophage T3 RNA polymerase | <enzyme> Used for the rapid generation of strand-specific RNA molecules that can be used for the identification of genes in hybridization experiments Registry number: EC 2.7.7.- Synonym: t3 RNA polymerase (26 Jun 1999) |
| cap II RNA(nucleoside-2'-)methyltransferase | <enzyme> Converts cap i-terminated mRNA to cap II-terminated mRNA Registry number: EC 2.1.1.- Synonym: cap II methylase (26 Jun 1999) |
| cap I RNA (nucleoside-2'-)methyltransferase | <enzyme> Converts cap 0-terminated mRNA to cap i-terminated mRNA Registry number: EC 2.1.1.- Synonym: cap I methylase (26 Jun 1999) |
| p68 RNA helicase | <enzyme> An RNA helicase isolated from uv-induced tumours in mice; amino acid sequence has been determined Registry number: EC 2.7.7.- Synonym: dead box helicase p68 (26 Jun 1999) |
| masked messenger RNA | <molecular biology> Long lived and stable mRNA found originally in the oocytes of echinoderms and constituting a store of maternal information for protein synthesis that is unmasked (derepressed) during the early stages of morphogenesis. In these early stages the rate of cell division is so rapid that transcription from the embryonic genome cannot occur. Undoubtedly not restricted to oocytes and the term can be applied to any mRNA which is present in inactive form. (18 Nov 1997) |
| ribosomal RNA | <molecular biology> A nucleic acid found in all living cells. Plays a role in transferring information from DNA to the protein-forming system of the cell. (16 Dec 1997) |
| messenger-like RNA | An ill-defined form of RNA, of high molecular weight, that never leaves the nucleus and is thought to be the precursor of messenger RNA. (05 Mar 2000) |