| prostate carcinoma | <radiology> Treatment: stages A and B: radical prostatectomy (prostate, seminal vesicles, part of bladder); some do simple prostatectomy for stage A, stage C: radiation therapy, stage D: orchiectomy and/or oestrogens stage A Tumour discovered incidentally in tissue removed for BPH, A1 Small focal involvement of one lobe, A2 Multifocal or diffuse carcinoma, Stage B Palpable carcinoma confined to prostate on digital exam, B1 Solitary nodule less than 1.5 cm, B2 Diffuse involvement of both lobes, Stage C Tumour extending through the prostate capsule; no metastasis, Stage D Metastases, usually to bone and/or pelvic lymph nodes (12 Dec 1998) |
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| prostate gland | A gland in the male that surrounds the neck of the bladder and urethra. The prostate contributes to the seminal fluid. (16 Dec 1997) |
| prostate-specific antigen | <tumour marker> A simple blood test used to detect prostate cancer in men. The test measures a specific antigen normally secreted by the prostate. If cancer is developing, the prostate secretes greater amounts of prostate-specific antigen. This test is recommended for men with an enlarged prostate and an increased risk of prostate cancer. It is an enzyme that is produced by epithelial cells of both benign and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer. It is a single chain 31 kilodalton glycoprotein with 240 amino acid residues and 4 carbohydrate side chains that is a kallikrein protease. It is found in normal seminal fluid and produced by the prostatic epithelial cells. Elevated levels in blood serum are associated with prostatic enlargement and prostatic adenocarcinoma, and this allows early detection of cancer in many cases. In about 70% of cases, the rise is due to a cancerous condition. No large scale clinical studies have been completed to assess the impact of testing on survival from prostate cancer, and the medical and economic value of testing remain uncertain. Acronym: PSA Registry number: EC 3.4.21.77 (22 Sep 2002) |
| nodular hyperplasia of prostate | Glandular and stromal hyperplasia occurring very commonly in the middle and lateral lobes of older men, forming nodules that may increasingly obstruct the urethra. Synonym: benign prostatic hypertrophy. (05 Mar 2000) |
| inferolateral surface of prostate | The surface of the prostate facing the body of the pubis and the pelvic diaphragm. Synonym: facies inferolateralis prostatae. (05 Mar 2000) |
| isthmus of prostate | The narrow middle part of the prostate anterior to the urethra. Synonym: isthmus prostatae. (05 Mar 2000) |
| elevator muscle of prostate | <anatomy> In the male, the most medial fibres of the levator ani (pubococcygeus) muscle that extend from the pubis into the fascia of the prostate. Synonym: musculus levator prostatae, elevator muscle of prostate. (05 Mar 2000) |
| fascia of prostate | The condensation of pelvic visceral fascia that encloses the prostate gland. Synonym: fascia prostatae. (05 Mar 2000) |
| female prostate | Term sometimes applied to the periurethral glands in the upper part of the urethra in the female. (05 Mar 2000) |
| lobe of prostate | One of the lateral lobes (right or left) or the middle lobe or isthmus of the prostate; in the adult the lobes are ill-defined. Synonym: lobus prostatae. (05 Mar 2000) |
| American Cancer Society | <address, organisation> American Cancer Society, National Headquarters, 1599 Clifton Road, NE, Atlanta, GA 30329 USA. Tel: 00 1 404 320-3333 (05 Feb 1998) |
| bladder cancer | The most common warning sign of bladder cancer is blood in the urine. The diagnosis of bladder cancer is supported by findings in the medical history and examination, blood, urine, and X-ray tests, and confirmed with a biopsy (usually during a cystoscope exam). Treatment of bladder cancer depends on the growth, size, and location of the tumour. (12 Dec 1998) |
| bladder cancer risks | Smoking is a major risk factor. Cigarette smokers develop bladder cancer 2-3 times more often than do nonsmokers. Quitting smoking reduces the risk of bladder cancer, lung cancer, several other types of cancer, and a number of other diseases as well. Workers in some occupations are at higher risk of developing bladder cancer because of exposure to carcinogens (cancer-causing substances) in the workplace. These workers include people in the rubber, chemical, and leather industries, as well as hairstylists, machinists, metal workers, printers, painters, textile workers, and truck drivers. (12 Dec 1998) |
| bone cancer | <oncology> A general term to imply malignant tumour growth in bone. (27 Sep 1997) |
| bovine cancer eye | A malignant squamous cell carcinoma of cattle, especially the Hereford breed, that originates in the conjunctival mucous membranes or the surrounding skin; it occurs principally in range cattle having unpigmented skin around the eye and living in regions of intense sunlight. (05 Mar 2000) |