| prostate-specific antigen | <tumour marker> A simple blood test used to detect prostate cancer in men. The test measures a specific antigen normally secreted by the prostate. If cancer is developing, the prostate secretes greater amounts of prostate-specific antigen. This test is recommended for men with an enlarged prostate and an increased risk of prostate cancer. It is an enzyme that is produced by epithelial cells of both benign and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer. It is a single chain 31 kilodalton glycoprotein with 240 amino acid residues and 4 carbohydrate side chains that is a kallikrein protease. It is found in normal seminal fluid and produced by the prostatic epithelial cells. Elevated levels in blood serum are associated with prostatic enlargement and prostatic adenocarcinoma, and this allows early detection of cancer in many cases. In about 70% of cases, the rise is due to a cancerous condition. No large scale clinical studies have been completed to assess the impact of testing on survival from prostate cancer, and the medical and economic value of testing remain uncertain. Acronym: PSA Registry number: EC 3.4.21.77 (22 Sep 2002) |
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| nodular hyperplasia of prostate | Glandular and stromal hyperplasia occurring very commonly in the middle and lateral lobes of older men, forming nodules that may increasingly obstruct the urethra. Synonym: benign prostatic hypertrophy. (05 Mar 2000) |
| inferolateral surface of prostate | The surface of the prostate facing the body of the pubis and the pelvic diaphragm. Synonym: facies inferolateralis prostatae. (05 Mar 2000) |
| isthmus of prostate | The narrow middle part of the prostate anterior to the urethra. Synonym: isthmus prostatae. (05 Mar 2000) |
| elevator muscle of prostate | <anatomy> In the male, the most medial fibres of the levator ani (pubococcygeus) muscle that extend from the pubis into the fascia of the prostate. Synonym: musculus levator prostatae, elevator muscle of prostate. (05 Mar 2000) |
| fascia of prostate | The condensation of pelvic visceral fascia that encloses the prostate gland. Synonym: fascia prostatae. (05 Mar 2000) |
| female prostate | Term sometimes applied to the periurethral glands in the upper part of the urethra in the female. (05 Mar 2000) |
| lobe of prostate | One of the lateral lobes (right or left) or the middle lobe or isthmus of the prostate; in the adult the lobes are ill-defined. Synonym: lobus prostatae. (05 Mar 2000) |
| Arneth formula | The normal, approximate ratio of polymorphonuclear neutrophils, based on the number of lobes in the nuclei, as follows: 1 lobe, 5%; 2 lobes, 35%; 3 lobes, 41%; 4 lobes, 17%; 5 lobes, 2%. (05 Mar 2000) |
| Bazett's formula | A formula for correcting the observed Q-T interval in the electrocardiogram for cardiac rate: corrected Q-T = Q-T sec/✓R -R sec. (05 Mar 2000) |
| Bernhardt's formula | <nutrition> A formula used to calculate the ideal weight, in kilograms, for an adult; it is the height in centimeters times the chest circumference in centimeters divided by 240. (14 Aug 2000) |
| Black's formula | A translation of Pignet's formula into British measurements: F = (W + C) -H; F is the empirical factor, W is the weight in pounds, C the chest girth in inches at full inspiration, and H the height in inches; a man is classed as very strong when F is over 120, strong between 110 and 120, good 100 to 110, fair 90 to 100, weak 80 to 90, very weak under 80. (05 Mar 2000) |
| Broca's formula | A fully developed man (30 years old) should weigh as many kilograms as he is centimeters in height over and above 1 meter. (05 Mar 2000) |
| Van Slyke's formula | The value obtained when the square root of the urine flow (when below 2 ml/min) is multiplied by the urine urea concentration and divided by the whole blood urea concentration; represents an old empirical adjustment for the effect of low urine flow on urea excretion; sometimes corrected for body size by dividing by some function of body weight or surface area. Later, plasma concentration was substituted for blood concentration in the calculation. The normal value is about 54 ml/min per 1.73 m2 in an adult person. Synonym: Van Slyke's formula. (05 Mar 2000) |
| Mall's formula | A formula for determining the age (in days) of a human embryo; calculated as the square root of its length (measured from vertex to breech) in millimeters multiplied by 100. (05 Mar 2000) |