| 영문 | thyroid hormone | 한글 | 갑상샘호르몬 |
|---|---|---|---|
| 설명 | 광의의 갑상선호르몬은 티록신(thyroxine(T4)), 삼요드티로닌(triiodothyronine (T3)), 티로칼시토닌(thyrocalcitonin)의 3가지중 하나를 말하나 대개의 경우 협의의 뜻으로 사용되며 이 경우 티록신과 삼요드티로닌을 지칭한다. 갑상선 호르몬은 거의 모든 몸세포에서의 바탕질대사에 관여하여 에너지생성을 증가시키고 성장 발육을 촉진한다. 이것은 뇌하수체에서 분비되는 갑상샘 자극호르몬에 의해 합성 및 분비가 촉진된다. 섭취하여 체내에 들어온 요오드가 능동운반에 의해 갑상샘세포내로 들어가 세포내에 있는 단백질인 갑상샘 글로블린과 결합하여 갑상샘호르몬으로 합성된다. 요오드가 3분자 결합한 것을 T3, 4분자 결합한 것을 T4라 부름. 분비되는 갑상선 호르몬중 90%이상이 T4이다. 혈중으로 분비된 갑상샘호르몬은 혈중 단백질과 결합하는데 대부분은 티론신결합글로블린과 결합하며 일부는 알부민과 결합한다. 전반적인 대사율을 촉진시키며 어린이에서는 성장을 촉진시킨다. 특히 어린이에서 몰단백질 합성을 촉진하며 뇌의 발달에 중요한 기능을 함으로써, 선천성 갑상샘저하증(cretinism)을 조기 발견하여 치료하지 못하면 정신지체가 유발된다. 갑상샘과다증의 증상은 체내 대사가 항진되어 식욕이 증가하나 체중이 감소하고 심장박동수가 증가하고 더위를 참지 못하며, 갑상샘기능저하증의 증상은 위와 반대로 식욕이 감소하고 체중이 증가하며 심장박동수가 감소하고 추위를 참지 못하며 피부에 단백질이 축적되어 점액부종이 유발된다. |
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| If | nec if necessary |
|---|---|
| NEC | National Electrical Code; necrotizing enterocolitis; neuroendocrine cell; neuroendocrine convertase;... |
| PFT | 1) Platelet Function Test 2) Pulmonary Function Test |
| LFA | left femoral artery; left frontal craniotomy; left fronto-anterior [fetal position]; leukocyte funct... |
| LFT | latex fixation test; latex flocculation test; left fronto-transverse [fetal position]; liver functio... |
| ventricular function, left | The haemodynamic and electrophysiological action of the left ventricle. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance. (12 Dec 1998) |
|---|---|
| ventricular function, right | The haemodynamic and electrophysiological action of the right ventricle. (12 Dec 1998) |
| path function | <chemistry> A property that is dependent on the path taken. (09 Jan 1998) |
| respiratory function tests | Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc. (12 Dec 1998) |
| mixed function oxidases | <enzyme> Catalyse the insertion of one oxygen atom of molecular oxygen into the organ substrate. Require a second substrate to donate electrons for the reduction of the second atom in the oxygen molecule to water. Registry number: EC 1.13.12. (12 Dec 1998) |
| modulation transfer function | <microscopy> A mathematical function that expresses the ability of an optical or electronic device to transfer signals faithfully as a function of the spatial or temporal frequency of the signal. The modulation transfer function is the ratio of percentage modulation of a sinusoidal signal leaving to that entering the device over the range of frequencies of interest. The modulation transfer function is usually presented as a graph of modulation transfer function versus log (frequency). For a square wave signal, the function is known as the CTF. Acronym: MTF (26 Mar 1998) |
| placental function tests | Methods used for the assessment of placental function. (12 Dec 1998) |
| contrast transfer function | <microscopy> A mathematical function that expresses the ability of an optical or electronic device to transfer signals faithfully as a function of the spatial or temporal frequency of the signal. The modulation transfer function is the ratio of percentage modulation of a sinusoidal signal leaving to that entering the device over the range of frequencies of interest. The modulation transfer function is usually presented as a graph of modulation transfer function versus log (frequency). For a square wave signal, the function is known as the CTF. Acronym: MTF (26 Mar 1998) |
| point-spread function | <microscopy> The mathematical representation of the image of a point source. For a diffraction-limited optical system operating in the absence of aberrations, the point-spread function is the Airy disk. See: three-dimensional diffraction pattern. (05 Aug 1998) |
| hepatic function impairment | The impaired ability of the liver to fulfill its role in metabolism. (27 Sep 1997) |
| split renal function test | A study performed to determine various functional parameters of one kidney compared to the contralateral kidney; ureteral catheters are inserted at cystoscopy into the ureter or renal pelvis bilaterally, and simultaneous measurements are made of urine flow rate, insulin, or PAH (if infused), endogenous creatinine, or various urinary solutes. Synonym: differential renal function test, split renal function test. (05 Mar 2000) |
| state function | <chemistry> A property that is independent of the pathway, this function can be used to define or specify the state of the system. (09 Jan 1998) |
| differential renal function test | A study performed to determine various functional parameters of one kidney compared to the contralateral kidney; ureteral catheters are inserted at cystoscopy into the ureter or renal pelvis bilaterally, and simultaneous measurements are made of urine flow rate, insulin, or PAH (if infused), endogenous creatinine, or various urinary solutes. Synonym: differential renal function test, split renal function test. (05 Mar 2000) |
| discriminant function | A particular combination of continuous variable test results designed to achieve separation of groups; e.g., a single number representing a combination of weighted laboratory test results designed to discriminate between clinical classes. (05 Mar 2000) |
| distribution function | <radiobiology> Function characterising the density of particles located at a given point in phase space (a combination of velocity and/or position coordinates) at a given time. The velocity-space distribution function gives the number of particles with a particular velocity, the position-space distribution function is synonymous with the particle density in position-space. Different combinations of position and spatial coordinates are useful in different problems. (09 Oct 1997) |