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  • intravascular coagulation
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  • intrinsic pathway of coagulation
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  • plasma coagulation factor
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  • coagulation
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  • coagulation factor
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  • coagulation factor
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  • coagulation factor deficiency
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  • coagulation factor inhibitor
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  • coagulation factors
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  • coagulation necrosis
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  • coagulation test
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  • coagulation,fibrinolytic system
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  • coagulation,intrinsic pathway
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CT calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ...
DIVBC disseminated intravascular blood coagulation
DIVC disseminated intravascular coagulation
FMFD V familial multiple coagulation factor deficiency V
F2R [blood coagulation] factor II receptor
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MLS Microphthalmia with linear skin defects
MOTT Mycobacteria Other Than Tuberculosis
NTD Neural Tube Defects
OND Other Neurological Diseases
SO significant other
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coagulation 1. <haematology> The process of clot formation.
2. <chemistry> The solidification of a sol into a gelatinous mass, an alteration of a disperse phase or of a dissolved solid which causes the separation of the system into a liquid phase and an insoluble mass called the clot or curd. Coagulation is usually irreversible.
3. <surgery> The disruption of tissue by physical means to form an amorphous residuum, as in electrocoagulation and photocoagulation.
Origin: L. Coagulatio
(18 Nov 1997)
coagulation factor <haematology> Group of plasma protein substances (Factor I-XIII) contained in the plasma, which act in concert to bring about blood coagulation. Many of the factors contain EGF like domains.
(29 Sep 1997)
coagulation factor XI <haematology> A plasma serine protease with an apple domain.
(18 Nov 1997)
coagulation necrosis A type of necrosis in which the affected cells or tissue are converted into a dry, dull, fairly homogeneous eosinophilic mass without nuclear staining, as a result of the coagulation of protein as occurs in an infarct; microscopically, the necrotic process involves chiefly the cells, and remnants of histologic elements (e.g., elastin, collagen, muscle fibres) may be recognizable, as well as "ghosts" of cells and portions of cell membranes; may be caused by heat, ischemia, and other agents that destroy tissue, including enzymes that would continue to alter the devitalised cellular substance.
(05 Mar 2000)
coagulation profile A test which measures the speed of blood coagulation at different steps of the coagulation pathway.
(27 Sep 1997)
coagulation time The time required for blood to coagulate; prolonged in haemophilia and in the presence of obstructive jaundice, some anaemias and leukaemias, and some of the infectious diseases.
Synonym: clotting time.
(05 Mar 2000)
coagulation vitamin An obsolete term for vitamin K.
(05 Mar 2000)
whole blood coagulation time Measurement of the time required by whole blood to produce a visible clot. Factors that could influence the test are all but III, vii, and xiii. Activation may be by contact with the glass tube or exposure to diatomaceous earth. Delay of onset of coagulation may be achieved by use of nonwettable plastic or silicone-coated glass tubes. It is used for monitoring heparin therapy and as a bedside screening test for deficiencies in the intrinsic coagulation pathway. "activated coagulation time" is sometimes referred to as act.
(12 Dec 1998)
heat coagulation test A test for measurement of protein in urine; albumin and globulin are coagulated by heat at an acid pH, and the amount of turbidity present provides a qualitative estimation of the degree of proteinuria.
(05 Mar 2000)
disseminated intravascular coagulation <haematology> Complication of septic shock in which endotoxin (from gram-negative bacteria) induces systemic clotting of the blood, probably indirectly through the effect of endotoxin on neutrophils.
It may also develop in other situations where neutrophils become systemically hyperactivated.
Acronym: DIC
(11 Jan 1998)
laser coagulation The coagulation of tissues using lasers. These lasers produce light in the visible green wavelength that is selectively absorbed by haemoglobin, and thus it is possible to seal bleeding blood vessels.
(12 Dec 1998)
light coagulation The coagulation of tissue by an intense beam of light, including laser (laser coagulation). In the eye it is used in the treatment of retinal detachments, retinal holes, aneurysms, haemorrhages, and malignant and benign neoplasms.
(12 Dec 1998)
lipoprotein-associated coagulation inhibitor Formerly known as anticonvertin; a protein that inhibits the extrinsic pathway of coagulation by binding to the tissue factor III-factor VII-Calcium-factor Xa complex.
(05 Mar 2000)
lupus coagulation inhibitor An antiphospholipid antibody found in association with systemic lupus erythematosus (lupus erythematosus, systemic), antiphospholipid syndrome, and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including foetal death and spontaneous abortion, as well as a variety of haematologic and neurologic complications.
(12 Dec 1998)
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