| 영문 | chronic obstructive pulmonary disease | 한글 | 만성폐쇄폐병 |
|---|---|---|---|
| 설명 | 만성적으로 기도의 폐쇄를 가져오는 병을 이르는 말. 대개 만성기관지염, 기관지 천식, 폐기종의 3가지 병을 말한다. 만성기관지염이란 기관지의 만성염증을 말한다. 기관지의 염증으로 인해서 기관지의 점막에 부종이 생기고 이로 인해서 기관지의 내경이 좁아져서 기도의 폐쇄를 가져온다. 대개 흡연과 밀접한 연관을 가지며, 호흡곤란, 기침, 그리고 가래(대개 색이 푸르고 점도가 높은 가래)가 증상으로 나타난다. 폐기종은 기관지의 벽을 지지하는 조직의 파괴에 의해서 기관지가 제 모양을 갖추지 못하고 무너지게 되어 기도의 폐쇄가 일어나는 병이다. 즉 기관지가 관 모양으로 팽팽하게 펴지는 것을 지지하는 조직의 파괴에 의해서 관모양으로 펴지지 못해 결국은 폐포내에 공기가 차고 폐포벽이 파열되고 기관지가 좁아지게 되는 병을 말한다. 기관지천식이란 여러 가지 자극에 대해서 기관지가 과민한 반응을 보여서 생기는 기관지의 가역적인 폐쇄를 의미한다. 즉 정상인에게서는 기관지의 폐쇄를 보이지 않는 자극에 대해서 기관지의 폐쇄가 생기고 그 자극이 없을 경우에는 기관지의 폐쇄가 없어지는 병을 말한다. |
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| 영문 | chronic active hepatitis | 한글 | 만성활동간염 |
|---|---|---|---|
| 설명 | B형 간염이나 비A형－비B형 간염의 속발증으로 나타나는 간의 만성염증이다. 같은 형태의 병이 선천성 또는 후천감마글로불린결핍증이나 어떤 종류의 약물 투여에 수반해서 나타날 수도 있다. 특징적으로 문맥부에 형질세포와 큰포식세포의 침윤, 조각괴사(간소엽 주변부 간세포의 파괴) 및 섬유증 등의 조직소견을 나타낸다. 병의 경과는 매우 다양하며 장기간의 무증상기를 보일 수도 있고 그 사이 사이에 황달, 전신쇠약, 식욕부진 및 발열 등의 증상이 나타나는 수가 있으며, 또 무월경증, 관절염, 피부발진, 혈관염, 갑상샘염, 콩팥사구체염, 궤양성대장염, 쉐그렌증후군 등 간 이외의 증상이 나타나는 수도 있고, 간경화증과 간기능상실로 진행되는 수도 있다. 자가면역메커니즘이 관여되는 것으로 추측되고 있다. |
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| NINCDS/ADRDA | National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Rel... |
|---|---|
| TORCH | toxoplasmosis, other [congenital syphilis and viruses], rubella, cytomegalovirus, and herpes simplex... |
| CPH | Certificate in Public Health; chronic paroxysmal hemicrania; chronic persistent hepatitis; chronic p... |
| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
| AL | absolute latency; acinar lumen; acute leukemia; adaptation level; albumin; alcoholism [and other dru... |
D factor
| persistent chronic hepatitis | A benign chronic hepatitis that may follow acute viral hepatitis A or B, or complicate bowel diseases; after six months, liver biopsy changes are mild, unlike active chronic hepatitis; rarely, if ever, progresses to cirrhosis, portal hypertension, or liver failure. (05 Mar 2000) |
|---|---|
| chronic | Persisting over a long period of time. Origin: L. Chronicus, Gr. Chronos = time (18 Nov 1997) |
| chronic abscess | A long-standing collection of pus surrounded by fibrous tissue. (05 Mar 2000) |
| chronic absorptive arthritis | Arthritis accompanied by pronounced resorption of bone with shortening and deformity, especially of the hands; when the deformity is extreme, the condition has also been termed arthritis mutilans. (05 Mar 2000) |
| chronic acholuric jaundice | <haematology> A hereditary disorder that leads to a chronic haemolytic anaemia due to an abnormality in the red blood cell membrane. This disorder is caused by a defective gene. Red cells are resistant to stress and rupture easily. Infants may appear jaundiced and pale. Fatigue, weakness and shortness of breath are other symptoms that may be seen in older patients. The spleen may also be enlarged. Treatment includes splenectomy (removal of the spleen). After this is accomplished the life-span of the red blood cells returns to normal. (27 Sep 1997) |
| chronic active hepatitis | <pathology> This is a form of continuing liver inflammation that results in liver cell death. Causes include viral infection (hepatitis D, hepatitis B, hepatitis C), autoimmune disease, drug ingestion or metabolic causes. Chronic active hepatitis will lead to hepatic failure and death in a small percentage of these patients. (27 Sep 1997) |
| chronic active inflammation | The coexistence of chronic inflammation and superimposed acute inflammation. (05 Mar 2000) |
| chronic active liver disease | Any of several types of hepatitis persisting for more than six months, often progressing to cirrhosis. Synonym: chronic active liver disease. (05 Mar 2000) |
| chronic adrenocortical insufficiency | Adrenocortical insufficiency usually as the result of idiopathic atrophy or destruction of both adrenal glands by tuberculosis, an autoimmune process, or other diseases; characterised by fatigue, decreased blood pressure, weight loss, increased melanin pigmentation of the skin and mucous membranes, anorexia, and nausea or vomiting; without appropriate replacement therapy, it can progress to acute adrenocortical insufficiency. Synonym: Addison's disease, addisonian syndrome, hyposupradrenalism, morbus Addisonii. (05 Mar 2000) |
| chronic African sleeping sickness | A chronic disease of humans caused by Trypanosoma brucei gambiense in northern and sub-Saharan Africa from Senegal east to Sudan and Uganda; characterised by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterised by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection. Synonym: chronic African sleeping sickness, chronic trypanosomiasis, West African sleeping sickness, West African trypanosomiasis. (05 Mar 2000) |
| chronic alcoholism | A pathologic condition, affecting chiefly the nervous and gastroenteric systems, associated with impairment in social and occupational functioning, caused by the habitual use of alcoholic beverages in toxic amounts. See: gamma alcoholism. (05 Mar 2000) |
| chronic allograft rejection | Immunologically mediated damage to the allograft, typically a kidney allograft, manifested by diffuse interstitial fibrosis glomerular changes, typically membranous and sclerotic in nature, as well as intimal fibrosis of the blood vessels with tubular atrophy and loss of tubular structures. (05 Mar 2000) |
| chronic anaphylaxis | A haemorrhagic and necrotizing inflammation developing in the ileum (and also the colon) of sensitised dogs when they are fed a second dose of the sensitizing material. Synonym: chronic anaphylaxis. (05 Mar 2000) |
| chronic anterior poliomyelitis | Muscular atrophy of the upper extremities and neck, in which there are long intermissions of quiescence or improvement; not to be confused with poliomyelitis virus infections. (05 Mar 2000) |
| chronic appendicitis | Fibrous adhesions, scarring, or deformity of the appendix following subsidence of acute appendicitis; fibrous obliteration of the distal lumen is not abnormal in older persons; term frequently used to refer to repeated mild attacks of acute appendicitis. (05 Mar 2000) |