| V-ONC | viral oncogene |
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| ERF | Education and Research Foundation; external rotation in flexion; Eye Research Foundation |
| ICR | [distance between] iliac crests; Institute for Cancer Research; Institute for Cancer Research [mouse... |
| ISR | information storage and retrieval; Institute for Sex Research; Institute of Surgical Research; insul... |
| OHR | occupational health research; Office of Health Research |
| nursing evaluation research | Research carried out by nurses that uses interviews, data collection, observation, surveys, etc., to evaluate nursing, health, clinical, and nursing education programs and curricula, and which also demonstrates the value of such evaluation. (12 Dec 1998) |
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| nursing methodology research | Research carried out by nurses concerning techniques and methods to implement projects and to document information, including methods of interviewing patients, collecting data, and forming inferences. The concept includes exploration of methodological issues such as human subjectivity and human experience. (12 Dec 1998) |
| nursing research | Research carried out by nurses, generally in clinical settings, in the areas of clinical practice, evaluation, nursing education, nursing administration, and methodology. (12 Dec 1998) |
| dental research | The study of laws, theories, and hypotheses through a systematic examination of pertinent facts and their interpretation in the field of dentistry. (12 Dec 1998) |
| operations research | A group of techniques developed to apply scientific methods and tools to solve the problems of decision making in complex organizations and systems. Operations research searches for optimal solutions in situations of conflicting goals and makes use of mathematical models from which solutions for actual problems may be derived. (12 Dec 1998) |
| epidemiologic research design | The form and structure of analytic studies in epidemiologic and clinical research. (12 Dec 1998) |
| united states agency for health care policy and research | An agency of the public health service established in 1990 to "provide indexing, abstracting, translating, publishing, and other services leading to a more effective and timely dissemination of information on research, demonstration projects, and evaluations with respect to health care to public and private entities and individuals engaged in the improvement of health care delivery.." it supersedes the national centre for health services research. (12 Dec 1998) |
| united states office of research integrity | An office of the united states public health service organised in june 1992 to promote research integrity and investigate misconduct in research supported by the public health service. It consolidates the office of scientific integrity of the national institutes of health and the office of scientific integrity review in the office of the assistant secretary for health. The ori is in the office of the assistant secretary for health and its director reports directly to the assistant secretary for health, department of health and human services. (ri newsletter, 1993 jan; 1(1):1) (12 Dec 1998) |
| recessive oncogene | <molecular biology> A single copy of this gene issufficient to suppress cell proliferation, the loss of both copies of the gene contributes to cancer formation. (09 Oct 1997) |
| viral oncogene | <molecular biology> A viral gene that contributes to cancer development in vertebrate hosts. (09 Oct 1997) |
| cellular oncogene | <molecular biology> A normal gene that, when mutated or improperly expressed, can cause cancer to develop. (09 Oct 1997) |
| c-oncogene | <molecular biology> A normal gene which has a tumour-producing insert that may have originated from a virus in it, turning it into a proto-oncogene. When these genes are sufficiently mutated, amplified, or over-expressed (transcribed too many times), they can begin to produce cancers. (05 Jan 1998) |
| proto-oncogene | <molecular biology> The normal, cellular equivalent of an oncogene, thus usually a gene involved in the signalling or regulation of cell growth. In general, cellular proto-oncogenes are prefixed with a c, rather than their abnormal viral counterparts, that are prefixed with a v, for example c myc and v myc. They are fragments of DNA, related to oncogenes but are the normal switches used to control growth and tissue repair. (06 Oct 1997) |
| proto-oncogene protein p21(ras) | Cellular protein encoded by the c-ras genes. The protein has GTPase activity and is involved in transmembrane signal transduction as a guanine nucleotide binding protein. Elevated levels of p21 c-ras have been associated with neoplasia. (12 Dec 1998) |
| proto-oncogene protein pp60(c-src) | <enzyme> Membrane-associated tyrosine-specific kinase encoded by the c-src genes. It has an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to pp60(v-src) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase. Registry number: EC 2.7.1.- (12 Dec 1998) |