| O&O | on and off |
|---|---|
| TTO | time trade-off [method] |
| Dmax | maximum denaturation; maximum diameter |
| MAC | MacConkey [broth]; major ambulatory category; malignancy-associated changes; maximum allowable conce... |
| MCP | maximum closure pressure; maximum contraction pattern; malanocortin receptor; melphalan, cyclophosph... |
| maximum velocity | The maximum rate of an enzyme-catalyzed reaction that can be achieved by progressively increasing the substrate concentration at a given enzyme concentration; in cases of substrate inhibition, Vmax is an extrapolated value in the absence of such inhibition; Cf.: Michaelis-Menten equation. The maximum initial rate of shortening of a myocardial fibre that can be obtained under zero load; used to evaluate the contractility of the fibre. (05 Mar 2000) |
|---|---|
| maximum voluntary ventilation | The volume of air breathed when an individual breathes as deeply and as quickly as possible for a given time (e.g., 15 sec.). Synonym: maximum breathing capacity. (05 Mar 2000) |
| tubular maximum | transport maximum |
| mitotic shake off method | <cell biology, procedure> A method of collecting cells in mitosis, so that the chromosomes can be examined and the karyotype determined. Many cultured cells round up during mitosis and so become less firmly attached to the culture substratum. Cells in mitosis thus can be removed into suspension by gentle shaking of the culture vessel, leaving the nonmitotic cells still attached. The number of cells that are in mitosis is usually increased by using a drug, such as colcemid that blocks mitosis at metaphase. (18 Nov 1997) |
| scrape-off layer | <radiobiology> Outer layer of a plasma which is affected (scraped off) by a divertor or limiter. That is, the outer layer of a magnetically confined plasma (ca. 2 cm thick) where the field lines penetrate a material surface (limiter or divertor plate) rather than close upon themselves. This region defines the outer limit of the plasma because any plasma crossing into the SOL is rapidly lost since transport along the field is much faster than that across the field. That is, particles follow these field lines into the material surface and are lost from the plasma. (09 Oct 1997) |
| set-off | 1. That which is set off against another thing; an offset. "I do not contemplate such a heroine as a set-off to the many sins imputed to me as committed against woman." (D. Jerrold) 2. That which is used to improve the appearance of anything; a decoration; an ornament. 3. A counterclaim; a cross debt or demand; a distinct claim filed or set up by the defendant against the plaintiff's demand. Set-off differs from recoupment, as the latter generally grows out of the same matter or contract with the plaintiff's claim, while the former grows out of distinct matter, and does not of itself deny the justice of the plaintiff's demand. Offset is sometimes improperly used for the legal term set-off. See Recoupment. 4. Same as Offset. 5. See Offset. Synonym: Set-off, Offset. Offset originally denoted that which branches off or projects, as a shoot from a tree, but the term has long been used in America in the sense of set-off. This use is beginning to obtain in England; though Macaulay uses set-off, and so, perhaps, do a majority of English writers. Origin: Set + off. Source: Websters Dictionary (01 Mar 1998) |
| slab-off | A process by which prism base-up is produced in the reading field of a spectacle lens through bicentric grinding. (05 Mar 2000) |
| slab-off lens | A spectacle lens with a base-up prism below; used in unequal myopia to equalise image displacement when reading. (05 Mar 2000) |
| nuclear run off assay | <investigation, procedure> Technique for determining which genes are being actively transcribed at a given moment in an experiment by extracting nuclear material and allowing transcription to continue, then analysing the resulting RNAs. (18 Nov 1997) |
| off | 1. On the farther side; most distant; on the side of an animal or a team farthest from the driver when he is on foot; in the United States, the right side; as, the off horse or ox in a team, in distinction from the nigh or near horse or ox; the off leg. 2. Designating a time when one is not strictly attentive to business or affairs, or is absent from his post, and, hence, a time when affairs are not urgent; as, he took an off day for fishing: an off year in politics. "In the off season." Off side. The right hand side in driving; the farther side. See Gee. In a general sense, denoting from or away from; as: 1. Denoting distance or separation; as, the house is a mile off. 2. Denoting the action of removing or separating; separation; as, to take off the hat or cloak; to cut off, to pare off, to clip off, to peel off, to tear off, to march off, to fly off, and the like. 3. Denoting a leaving, abandonment, departure, abatement, interruption, or remission; as, the fever goes off; the pain goes off; the game is off; all bets are off. 4. Denoting a different direction; not on or towards: away; as, to look off. 5. Denoting opposition or negation. "The questions no way touch upon puritanism, either off or on." (Bp. Sanderson) From off, off from; off. "A live coal..taken with the tongs from off the altar." . Off and on. Not constantly; not regularly; now and then; occasionally. To divide and practice a regiment or company in the several formations, preparatory to marching to the general parade for field exercises. To be well off, to be in good condition. To be ill off, To be badly off, to be in poor condition. Origin: OE. Of, orig. The same word as R. Of, prep, AS. Of, adv. & prep. 194. See Of. Source: Websters Dictionary (01 Mar 1998) |
| off-label | Use of a drug for a disease or condition other than the indication for which it was approved by the FDA. For example: many doctors prescribe paromomycin (humatin) for cryptosporidiosis, although it is not approved for treating this disease. (09 Oct 1997) |
| off-label use | In the United States, the regulations of the Food and drug administration (FDA) permit physicians to prescribe approved medications for other than their intended indications. This practice is known as off-label use. (12 Dec 1998) |
| off-road motor vehicles | Motorised, recreational vehicles used on non-public roads. They include all-terrain vehicles, dirt-bikes, minibikes, motorbikes, trailbikes, and snowmobiles. Excludes motorcycles, which are considered public road vehicles. (12 Dec 1998) |
| on-off phenomenon | A state in the treatment of Parkinson's disease by l-dopa, in which there is a rapid fluctuation of akinetic (off) and choreoathetotic (on) movements. (05 Mar 2000) |
| ordered on-random off mechanism | A scheme for substrate binding and product release for multisubstrate enzymes; for a two-substrate two-product enzyme with this mechanism, the individuals have to bind to the enzyme in a distinct order; however, once the products are formed they may dissociate from the enzyme in either order. It has been suggested that pyruvate kinase has such a mechanism. The random on-ordered off mechanism is simply the reverse of this mechanism. (05 Mar 2000) |