| new south wales | A state in southeastern Australia. Its capital is sydney. It was discovered by captain cook in 1770 and first settled at botany bay by marines and convicts in 1788. It was named by captain cook who thought its coastline resembled that of south wales. (12 Dec 1998) |
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| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| beige mouse | A mouse strain typified by beige hair and lymphadenopathy, reticulum cell neoplasms and giant lysosomal granules in leukocytes. May be the murine equivalent of Chediak Higashi syndrome of man. (18 Nov 1997) |
| mammary tumour viruses, mouse | The type species of mammalian type b retroviruses (retroviruses type b, mammalian) commonly latent in mice. It causes mammary adenocarcinoma when in a genetically susceptible strain of mice and when the appropriate hormonal influences operate. (12 Dec 1998) |
| water mouse | <zoology> Any one of several species of mice belonging to the genus Hydromys, native of Australia and Tasmania. Their hind legs are strong and their toes partially webbed. They live on the borders of streams, and swim well. They are remarkable as being the only rodents found in Australia. Source: Websters Dictionary (01 Mar 1998) |
| mouse | Origin: OE. Mous, mus, AS. Mus, pl. M<ymac/s; akin to D. Muis, G. Maus, OHG. & Icel. Mus, Dan. Muus, Sw. Mus, Russ. Muishe, L. Mus, Gr. My^s, Skr. Mush mouse, mush to steal. 277. Cf. Muscle, Musk. 1. <zoology> Any one of numerous species of small rodents belonging to the genus Mus and various related genera of the family Muridae. The common house mouse (Mus musculus) is found in nearly all countries. The American white-footed, or deer, mouse (Hesperomys leucopus) sometimes lives in houses. See Dormouse, Meadow mouse, under Meadow, and Harvest mouse. 2. A knob made on a rope with spun yarn or parceling to prevent a running eye from slipping. Same as 2d Mousing. 3. A familiar term of endearment. 4. A dark-coloured swelling caused by a blow. 5. A match used in firing guns or blasting. Field mouse, Flying mouse, etc. See Field, Flying, etc. Mouse bird, the piece of beef cut from the part next below the round or from the lower part of the latter. Synonym: mouse buttock. Source: Websters Dictionary (01 Mar 1998) |
| mouse antialopecia factor | A member of the vitamin B complex necessary for growth of yeast and of mice, absence from the diet causes hair loss and dermatitis in mice. (27 Sep 1997) |
| mouse cancer | Any of various types of malignant neoplasms that occur naturally in mice, especially in certain inbred "c. Strains" used for research studies. (05 Mar 2000) |
| mouse-ear | <botany> The forget-me-not (Myosotis palustris) and other species of the same genus. A European species of hawkweed (Hieracium Pilosella). Mouse-ear chickweed, a name of two common species of chickweed (Cerastium vulgarium, and C. Viscosum). Mouse-ear cress, a low cruciferous herb (Sisymbrium Thaliana). All these are low herbs with soft, oval, or obovate leaves, whence the name. Source: Websters Dictionary (01 Mar 1998) |
| mouse encephalomyelitis | Encephalomyelitis due to the mouse encephalomyelitis virus (a species of Enterovirus) which is not pathogenic in monkeys or in man, but attacks mouse colonies and causes a flaccid paralysis, usually of the hind limbs. Synonym: mouse poliomyelitis, Theiler's disease. (05 Mar 2000) |
| mouse encephalomyelitis virus | A virus of the genus Enterovirus, family Picornaviridae, normally associated with inapparent infections and found in the intestinal tracts of infected mice, occasionally causing mouse encephalomyelitis in experimentally inoculated susceptible mice. Synonym: mouse poliomyelitis virus. (05 Mar 2000) |