| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
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| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| american dental association | Professional society representing the field of dentistry. (12 Dec 1998) |
| american hospital association | A professional society in the united states whose membership is composed of hospitals. (12 Dec 1998) |
| american medical association | Professional society representing the field of medicine. (12 Dec 1998) |
| american nurses' association | Professional society representing the field of nursing. (12 Dec 1998) |
| american speech-language-hearing association | A professional society concerned with the diagnosis, prevention, treatment, and remediation of speech, language, and hearing disorders. (12 Dec 1998) |
| association | 1. <neurology> Correlation involving a high degree of modifiability and also consciousness. 2. <genetics> The occurrence together of two or more phenotypic characteristics more often than would be expected by change. To be distinguished from linkage. 3. In dysmorphology, the nonrandom occurrence in two or more individuals of multiple anomalies not known to be a polytopic field defect, sequence or syndrome. Origin: L. Associatio (18 Nov 1997) |
| association areas | Generic term denoting the large expanses of the cerebral cortex that are not sensory or motor in the customary sense, but are involved in advanced stages of sensory information processing, multisensory integration, or sensorimotor integration. See: cerebral cortex. Synonym: association areas. (05 Mar 2000) |
| association constant | <chemistry> Reciprocal of dissociation constant. A measure of the extent of a reversible association between two molecular species at equilibrium. (18 Nov 1997) |
| association cortex | Generic term denoting the large expanses of the cerebral cortex that are not sensory or motor in the customary sense, but are involved in advanced stages of sensory information processing, multisensory integration, or sensorimotor integration. See: cerebral cortex. Synonym: association areas. (05 Mar 2000) |