| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
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| MMAA | mini-microaggregates of albumin |
| MMS | mass mammographic screening; Master of Medical Science; methyl methanesulfonate; Mini-Mental State |
| MMSE | mini-mental status examination |
| 3MS | modified mini-mental state examination |
| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
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| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| anaesthesia, closed-circuit | Inhalation anaesthesia where the gases exhaled by the patient are rebreathed as some carbon dioxide is simultaneously removed and anaesthetic gas and oxygen are added so that no anaesthetic escapes into the room. Closed-circuit anaesthesia is used especially with explosive anaesthetics to prevent fires where electrical sparking from instruments is possible. (12 Dec 1998) |
| closed anaesthesia | Inhalation anaesthesia in which there is total rebreathing of all exhaled gases, except carbon dioxide which is absorbed; gas flow into the anaesthetic circuit consists only of oxygen, in amounts equal to the patient's metabolic consumption, plus small amounts of other gases (e.g., nitrous oxide) which undergo continued uptake by and distribution in the patient. (05 Mar 2000) |
| closed-angle glaucoma | angle-closure glaucoma |
| closed bite | <dentistry> A malocclusion where your upper teeth cover your lower teeth when you bite down. This is also called a deep bite. (08 Jan 1998) |
| closed chain compound | Any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic chemistry where: 1) numerous compound's contain rings of carbon atoms (carbocyclic compound's) or carbon atoms plus one or more atoms of other types (heterocyclic compound's), usually nitrogen, oxygen, or sulfur; 2) where the atoms in the ring are all of the same element (homocyclic or isocyclic compound); 3) where the ring is saturated or contains nonconjugated double bonds (alicyclic compound), the compound is similar in properties to the corresponding acyclic compound (e.g., cyclohexane resembles hexane); 4) where the ring contains conjugated double bonds in a closed loop in which there are 4n + 2 (where n is an integer) delocalised π electrons (Huckel's rule) (aromatic compound; e.g., benzene, pyridine), it is more stable than the corresponding saturated ring and exhibits unusual chemical properties characteristic of itself and not of other types of rings or of acyclic compound's. These aromatic compounds have the ability to sustain an induced ring current. Synonym: closed chain compound, ring compound. (05 Mar 2000) |
| closed chest massage | Rhythmic compression of the heart between sternum and spine by depressing the lower sternum backward with the heels of the hands, the patient lying supine. Synonym: external cardiac massage. (05 Mar 2000) |
| closed circle | A circuit for administration of an inhalation anaesthetic in which there is complete rebreathing with carbon dioxide absorption. (05 Mar 2000) |
| closed circuit method | A method for measuring oxygen consumption in which the subject rebreathes an initial quantity of oxygen through a carbon dioxide absorber and the decrease in the volume of oxygen being rebreathed is noted. (05 Mar 2000) |